小儿急性中枢性呼吸性衰竭辅以纳络酮治疗的疗效观察  

CLINICAL OBSERVATION ON EFFECT OF NALOXONE HYDROCHLORIDE ON YOUNG CHILDERN OF CENTRAL RESPIRATORY FAILURE CASES

作　　者：李文君[1,2,3] 张裕民[1,2,3] 刘亚红[1,2,3] 张英茹[1,2,3] 

机构地区：[1]河北省张家口教育学院临床医学系,张家口075000 [2]河北省张家口地方病防治所 [3]河北北方学院附属第一医院儿科

出　　处：《现代预防医学》2009年第23期4590-4591,共2页Modern Preventive Medicine

摘　　要：[目的]探讨纳络酮治疗中枢性呼吸衰竭的疗效。[方法]将120例急性中枢性呼吸衰竭的患儿随机分为治疗组和对照组,分别给予常规疗法加纳络酮和常规疗法治疗。[结果]治疗组有效率为88.3%,对照组有效率为75%,两组疗效差异有统计学意义(χ2=3.55,P﹤0.05)。[结论]纳络酮在治疗小儿急性中枢性呼吸衰竭上疗效确切,值得推广。[Objective]To study the clinical effect of naloxone hydrochloride on acute central respiratory failure. [Methods] 120 acute central respiratory failure cases were divided into control group and treatment group randomly. The patients in control group were treated by the conventional therapy, and the patients in treatment group were treated by the conventional therapy plus naloxone hydrochloride. [Results] The effective rate in the treatment group was 88.3%, correspondingly the effective rate was 75.% in the control group. There was a remarkable significance in the treatment effect between the two groups （χ^2 = 3.55, P﹤0.05）. [Conclusion] Naloxone hydrochloride may serve as a conventional drug to the acute central respiratory failure.

关 键 词：纳络酮 急性呼吸衰竭 

分 类 号：R969.4[医药卫生—药理学]