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作 者:高国一[1] 姜范波 杨玲 平措扎西[1] 华桑 李奎[1] 汪建
机构地区:[1]中国科学院北京基因组研究所,北京100029 [2]深圳华大基因研究院
出 处:《内蒙古医学院学报》2009年第5期445-447,456,共4页Acta Academiae Medicinae Neimongol
基 金:中国科学院知识创新工程重要方向项目(KSCX2-YW-R-76)
摘 要:目的:研究内蒙古东乌珠穆沁旗地区蒙古族正常人群骨量分布情况,确定峰值骨量,分析其年龄段变化规律。为本地区制定骨质疏松诊断标准提供科学依据。方法:选择内蒙古东乌珠穆沁旗蒙古族健康男女901名,年龄为20-79岁。以10岁为一年龄段,对男女分别进行分组。用美国Alara公司提供的MetriscanTM指骨骨密度仪,对非习惯性用手的第2、3、4手指进行测量,取三个手指的平均骨密度值。数据采用SPSS11.0软件进行统计学分析。结果:内蒙古东乌珠穆沁旗蒙古族女性峰值骨量在30-39岁年龄段,男性在40-49岁年龄段。女性60-69岁年龄段骨量丢失15.01%,在70-79岁年龄段骨量丢失21.09%,达2.328SD;男性在70-79岁年龄段骨量丢失11.04%。男女峰值骨密度分别为0.3994g/cm3和0.3776g/cm3。男性各年龄段骨密度值均高于女性。结论:放射吸收法测量内蒙古东乌珠穆沁旗地区健康人群峰值骨量和骨量丢失规律符合骨质疏松流行病学发病率,但晚于国内相关报道。本研究结果为内蒙古蒙古族骨密度研究提供了参考数据和资料。Objective: To conduct research on bone mineral density (BMD) in healthy mongolian people group in inner mongolia . To provide basic data for osteoporosis diagnostic criteria by defining the peak of bone mass and disclosing its change with age in inner mongolia. Methods:901 healthy mongolia women and men in inner mongolia, all aged from 20 to 79, every 10 - year - old age as a group, subdivided by sex. Measuring the BMD value of the 2nd,3rd,4th finger of the non -habitual hand with the metriscanTM bone density system provided by alara company . Take three fingers average bone mineral density as the final BMD value, Statistical analysis was using by the SPSSI 1.0 . Resuits :mongolia women peak bone mass appears in the age of 30-39 and men peak bone mass appears in the age of 40 -49. The inner mongolia women loss bone mass of 15. 01% in the age of 60 -69, loss bone mass of 21.09% in the age of 70-79. Inner mongolia men loss bone mass of 11.04% in the age of 70-79. The peaks of bone mass for male and female mongolian were 0.3994g/cm^3 respeetirely and 0. 3776g/cm^3. Bone mineral density values of male were higher than female in all ages ( P 〈 0.05 ). Conclusion: Radiographic absorptiometry measurement of peak bone mass and the law of bone loss in healthy mongolia were consistent with the epidemiological incidence of osteoporosis previously reported The results provide data and information for further researches on bone.
关 键 词:骨密度值 健康人群 骨量丢失百分率 Metriscan骨密度仪
分 类 号:R336[医药卫生—人体生理学]
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