银杏制剂治疗颈动脉粥样硬化超声学观察  

Effects of Ginkgo Biloba Extract(Ginkgo Leaf Dripping Pills) on Carotid Atherosclerosis

作　　者：冯宏业[1] 金丽华[1] 游龙武[1] 梁玉宏[1] 

机构地区：[1]广东省深圳市第二人民医院神经内科,518035

出　　处：《医药世界》2009年第1期7-8,共2页Medicine World

基　　金：广东省中医药局课题(编号:2008277)

摘　　要：目的:观察银杏制剂对颈动脉粥样斑块的临床疗效。方法:选择颈动脉粥样斑块患者80例,随机分为两组。治疗组40例,服用银杏叶滴丸300mg,3次/d;对照组40例,服用肠溶阿司匹林片100mg,1次/d。疗程6个月。治疗前后用彩色多普勒超声检测颈动脉内中膜(IMT)厚度、计算斑块面积、Crouse斑块积分、血流动力学参数。结果:治疗组颈动脉IMT、斑块总积分、斑块面积均有改善,颈动脉血流改善,阻力减少,与对照组相比有统计学差异(P<0.05)。结论:银杏制剂有一定的消减及稳定动脉粥样硬化斑块的作用。Objective：To determine effects of Ginkgo Biloha Extract （GBE） on carotid atherosclerotic plaques. Methods：Eighty patients with carotid atherosclerosis （CAS） were randomly assigned to a therapeutic group and a control group. Forty Patients in the therapeutic group were orally administrated by Ginkgo Leaf Dripping Pills （GLDPs） 300 mg tid while forty patients in the control group were orally administrated by tablet enteric coated aspirin 100 mg qd. The length of treatment course in the two groups was six months. The intima-media thiekness （ITM）, area of carotid plaques, Crouse integrals, and blood flow parameters of carotid arteries were tested using color Doppler ultrasound imaging before and after treatment. Results ： After treatment, the IMT ,Crouse integrals, plaque area ,and carotid resistance were significantly lower in the therapeutic group than those in the control group （P〈0. 05）. Conclusions ：GBE can reduce and stabilize the atherosclerotic plaques.

关 键 词：颈动脉疾病/中药疗法/超声检查 粥样硬化/中药疗法/超声检查 银杏素/治疗应用 随机对照试验[文献类型] 人类 

分 类 号：R543.4[医药卫生—心血管疾病]