Synthesis and Biological Activities of α-Amino Acylamines Derivatives Containing Furan and Pyridine Ring  

作　　者：XU Yan~ XUE Si-jia 

机构地区：[1]Department of Chemistry, Shanghai Normal University, Shanghai 200234, P R. China

出　　处：《Chemical Research in Chinese Universities》2009年第6期846-850,共5页高等学校化学研究（英文版）

基　　金：Supported by the National Natural Science Foundation of China(No.20672073);Shanghai Leading Academic Discipline Project,China(No.T0402)

摘　　要：In order to find better herbicidal activity and fungicidal activity of a-amino acid derivatives, we introduced furan rings and pyridyl groups to seven different a-amino acids to form a series of 14 novel a-amino acylamines derivatives via dicyclohexylcarbodiimide/4-dimethylaminopyridine（DCC/DMAP） coupling method. The structures of all the compounds prepared were confirmed by IR, LC/MS, IH NMR, and elemental analysis. The herbicidal and fungicidal results show that some compounds containing glycine and valine substrate have good activities.In order to find better herbicidal activity and fungicidal activity of a-amino acid derivatives, we introduced furan rings and pyridyl groups to seven different a-amino acids to form a series of 14 novel a-amino acylamines derivatives via dicyclohexylcarbodiimide/4-dimethylaminopyridine（DCC/DMAP） coupling method. The structures of all the compounds prepared were confirmed by IR, LC/MS, IH NMR, and elemental analysis. The herbicidal and fungicidal results show that some compounds containing glycine and valine substrate have good activities.

关 键 词：Amino acid Furan ring Pyridyl group Herbicidal and fungicidal activity 

分 类 号：TQ457.29[化学工程—农药化工] O623.736[理学—有机化学]