左旋卡尼汀治疗维持性腹膜透析患者慢性心衰的临床观察  

L-carnitine Treatment of Maintenance Peritoneal Dialysis Patients With Chronic Heart Failure Clinical

作　　者：曲廖准[1] 

机构地区：[1]广东汕头市中心医院(中山大学附属汕头医院),515031

出　　处：《中国实用医药》2009年第34期46-47,共2页China Practical Medicine

摘　　要：目的观察左卡尼丁对腹膜透析患者慢性心衰的临床疗效。方法选择本院维持性腹膜透析慢性心衰患者130例,分为治疗组和对照组,相同基础治疗同时,治疗组给予静脉注射左卡尼汀每天1次,每次1.0g,连续用14d,观察两组用药前后心衰症状及心功能指标变化。结果两组前后心衰症状及心功能指标均得以改善,但治疗组疗效优于对照组;治疗组总有效率90.8%;对照组总有效率67.7%,以上差异具统计学意义(P<0.05)。结论左卡尼汀治疗维持性腹膜透析患者慢性心衰临床疗效高于即往采用洋地黄等对症式治疗。Objective To observe the left-carnitine in peritoneal dialysis patients with chronic heart failure clinical efficacy. Methods Hospital maintenance peritoneal dialysis patients with chronic heart failure, 130 patients divided into treatment group and control group, the same basic therapy, the treatment group received intravenous injection of L-eamitine a day a time for 14 days, each 1.0 g, were obscrved before and after treatment of heart failure symptoms and heart function parameters change. Results The results of the two groups before and after the symptoms of heart failure and cardiac function parameters were improved, but the efficacy of the treatment group than the control group; treatment group, the total efficiency of 90.8% ; the control group, the total efficiency of 67.7%, these differences statistically significant （ P 〈 0.05 ）. Conclusion L-carnitine treatment of maintenance peritoneal dialysis patients with chronic heart failure clinical use of digitalis other than that to the treatment of symptomatic type.

关 键 词：腹膜透析 左旋卡尼汀 慢性心衰 

分 类 号：R541.6[医药卫生—心血管疾病] R459.5[医药卫生—内科学]