茅莓对大鼠非细菌性前列腺炎的影响  

Effects of Rubus parvifoliusl extracts on nonbacterial prostatitis in the rats

作　　者：梁荣感[1] 毛庭枝[1] 侯巧燕[1] 杨成芳[1] 张均智[1] 

机构地区：[1]桂林医学院,广西桂林541004

出　　处：《广西植物》2009年第6期860-862,811,共4页Guihaia

摘　　要：采用角叉菜胶和消痔灵制备大鼠非细菌性前列腺炎病理模型,研究茅莓提取物对大鼠非细菌性前列腺炎的影响。取前列腺炎模型大鼠随机分为模型对照组、茅莓水提物高(5.0 g/kg)、低剂量组(2.5 g/kg)、茅莓醇提物高(5.0 g/kg)、低剂量组(2.5 g/kg),各组灌胃给药每天2次,连续28 d,观察大鼠前列腺湿重、指数及病理组织检查等指标的变化。结果表明:茅莓能抑制前列腺炎模型大鼠前列腺腺体增重(P<0.05),减轻炎性细胞浸润和损伤(P<0.05),对大鼠非细菌性前列腺炎有一定的治疗作用。Effects of Rubus parvifoliusl extracts on non-bacterial prostatitis induced by carrageenan xiaozhiling in the rats were studied. Non-bacterial prostatitis rats induced by carrageenan and Xiaozhiling were randomly divided into control group,high dose group（5.0 g/kg）and low-dose group（2. 5 g/kg）of water extracts of R. parvifoliusl,high-dose（5.0 g/kg）and low-dose groups（2. 5 g/kg）of alcohol extracts of Rubuparvifoliusl; the extract of R. parvifoliusl was administered to rats by gavage,twice a day,for consecutively 28 days. The changes in wet weight of prostate,prostate index, histological examinations and other indicators were observed on the rats. Results showed that： Extracts of R. parvifoliusl could decrease gland weight gained in the prostatitis rats（P〈0. 05）,reduce infiltration of inflammatory cells and injury（P〈0. 05）, and have certain therapeutic effects on non-bacterial prostatitis in the rats.

关 键 词：茅莓 非细菌性前列腺炎 角叉菜胶 消痔灵 

分 类 号：Q946[生物学—植物学]