提高甲状腺功能低下早产儿140例生活质量临床研究  

Clinical research on improving life quality of 140 premature infants with hypothyroidism

作　　者：张学花[1] 宋嘉[1] 邢韦韦[1] 袁久莉[1] 

机构地区：[1]山东大学附属省立医院,山东济南250021

出　　处：《齐鲁护理杂志》2009年第11期1-2,共2页Journal of Qilu Nursing

摘　　要：目的:探讨提高甲状腺功能低下早产儿生活质量的有效方法。方法:选取早产儿140例,应用放射免疫法检测生后第7天和第28天血清三碘甲状腺原氨酸、甲状腺素和促甲状腺素,并对早产儿的黄疸持续时间、体重增长速度、每日大便次数、吃奶情况进行观察比较。结果:①56例早产儿生后第7天时存在甲状腺激素水平降低,为T3和(或)T4降低,TSH升高或降低或正常。13例早产儿生后第28天时仍存在甲状腺激素水平降低。②甲状腺激素水平降低早产儿高胆红素血症持续时间延长,体重增长缓慢,每日大便次数减少,奶量少,与甲状腺功能正常早产儿相比,差异有统计学意义(P<0.05)。结论:早产儿生后可能存在一过性甲状腺功能低下,并有相应的临床表现。应加强护理,密切注意患儿黄疸、大便、吃奶等情况,及时给予退黄疸、促进排便,并加强喂养,选择合适的喂养方式,必要时给予静脉营养,提高早产儿的生活质量。Objective： To explore the effective method to improve life quality of premature infants with hypothyroidism. Methods： Radioimmunoassay was applied to detecting serum triiodothyronine, thyroxine and thyrotrophin of the selected 140 premature infants with hypothyroidism on the 7th and 28th day, and the duration of jaundice in premature infants, growth rate of budy weight, daily stool frequency and breast feeding were observed and compared. Results ： The level of thyroid hormone （ T3 and （ or） T4 ） of 56 premature infants declined and TSH increase or decrease or to be normal on the 7th day after birth; the level of thyroid hormone of the other 13 premature infants was still low on the 28th day after birth. The duration of hyperbilirubinemia prolonged, growth of body weight slowed, daily stool frequency reduced and feeding was less in premature infants with lower level of thyroid hormone and their differences were statistically significant compared with the premature infants who had normal thyroid function （ P 〈 0.05 ） . Conclusion ： The transient hypothyroidism may happen to preterm infants after birth and there are also some corresponding clinical manifestations. Much attention should be paid to observing jaundice, stool, feeding, etc. , and timely comprehensive treatment and nursing care should be given to preterm infants to alleviate jaundice, help defecation and strengthen feeding. Intravenous nutrition will be used if necessary so as to improve the quality of life of preterm infants.

关 键 词：早产儿 甲状腺功能低下 生活质量 护理 

分 类 号：R473.5[医药卫生—护理学]