CD_4分子对胸腺细胞发育的影响  

The Effects Of CD 4 On he Development Of Thymocytes

作　　者：郭亚平[1] 肖光倩[1] 

机构地区：[1]川北医学院微生物学教研室

出　　处：《川北医学院学报》1998年第3期10-11,共2页Journal of North Sichuan Medical College

摘　　要：本文应用小鼠体内注射抗Ｌ３Ｔ４ＭＣＡｂ封闭Ｔ细胞表现ＣＤ４分子，观察胸腺细胞数量及功能，结果显示：在一定抗Ｌ３Ｔ４ＭＣＡｂ剂量范围内，胸腺细胞总数与功能下降。胸腺双阳性细胞（ＤＰ），ＣＤ４单阳性细胞（ＣＤ４ＳＰ）数量下降，ＣＤ８单阳性细胞（ＣＤ８ＳＰ）。Abstract The number and function of thymocytes were investigated by blocking CD 4 on the surface of T lymphocytes with intra abdominal injection of anti L 3L 4McAb.The results showed that,in certain doses of anti L 3L 4McAb,the number and function of thymocytes,DP cells and CD 4SP cells decreased,however that of CD 8P cells increased. Anti L 3L 4McAb CD TCell Development

关 键 词：CD4分子 胸腺 细胞发育 

分 类 号：R392.12[医药卫生—免疫学]