电喷雾解吸电离质谱法测定纺织品中致癌性芳香胺  

Detection of Carcinogenic Aromatic Amines in Textiles by Desorption Electrospray Ionization Mass Spetrometry

作　　者：韩京[1] 杨水平[1] 张燮[1] 张丽丽[2] 陈焕文[1,2] 李建强[1] 

机构地区：[1]东华理工大学化学生物与材料科学学院,江西抚州344000 [2]吉林大学化学学院,吉林长春130021

出　　处：《岩矿测试》2009年第6期507-513,共7页Rock and Mineral Analysis

基　　金：国家自然科学基金项目资助(20505003);北京市财政项目资助(XM-00001783050811002)

摘　　要：用甲醇-水-乙酸（体积比49∶49∶2）混合溶液作为喷雾溶剂,在优化实验条件下,将电喷雾解吸电离质谱（DESI-MS）用于各种质地纺织品中24种致癌性芳香胺的非破坏性快速检测,均获得满意结果。分析实际样品时,由于该方法无需样品预处理,单个样品单一指标的检测不到30 s,大大节省了分析时间,提高了分析效率。同时借助串联质谱的特异性,能够有效地避免实验结果的假阳性。方法对大部分芳香胺具有较高的灵敏度,二级质谱中特征离子的检出限一般为10^-9g/kg。建立的方法能灵敏、快速、无损检测纺织品中的致癌芳香胺,精密度较好,对同一样品10次测量结果的相对标准偏差为5%-10%。Using a mixture of methanol/water/acetic acid （ volume ratio of 49 ： 49 ： 2 ） as the electrospray liquid and under the optimized experimental condition, 24 kinds of carcinogenic aromatic amines in various textures of textile samples were directly and non-destructively detected by desorption electrospray ionization mass spectrometry（DESI-MS） with satisfactory results. The mean analysis time for a single analyte in a sample was about 30s, more efficient due to without sample pretreatment. Furthermore, in virtue of the special performances of tandem-MS, the false positive results could be effectively eliminated. The method provides the advantages of high sensitivity （typical detection limit of 10^-9 g/kg rang for most aromatic amines）, high precision （5% - 10% RSD, n = 10） and more efficiency. The method has been applied to the direct and non-destructive determination of carcinogenic aromatic amines in various textures of textile samples.

关 键 词：电喷雾解吸电离(DESI) 串联质谱 离子阱质谱 无损检测 芳香胺 纺织品 

分 类 号：O657.63[理学—分析化学] O623.73[理学—化学]