抗SSA和抗RNP在系统性红斑狼疮中的意义  

The significance of anti-SSA antibody and anti-RNP antibody in systemic lupus erythematosus

作　　者：李晓霞[1] 杨国强[2] 史丽璞[2] 

机构地区：[1]郑州市儿童医院,河南郑州450003 [2]郑州人民医院,河南郑州450003

出　　处：《中国医药导报》2009年第34期20-21,共2页China Medical Herald

摘　　要：目的:探讨抗SSA和抗RNP在系统性红斑狼疮(SLE)中出现的几率。方法:采用免疫双扩散法(ID)和免疫印迹法(IBT)检测抗SSA、抗RNP。结果:用ID法、IBT法检测系统性红斑狼疮患者抗SSA阳性率高于抗RNP(P<0.05),ID法检测抗SSA,其特异性高于IBT法。结论:联合使用ID法和IBT法检测抗SSA和抗RNP,可以提高系统性红斑狼疮诊断的正确性,减少误诊、漏诊。Objective： To investigate the probability of the expression of anti-SSA antibody and anti-RNP antibody in systemic lupus erythematosus. Methods： Anti-SSA antibody and anti-RNP antibody were measured by ID and IBT. Results： Positive anti-SSA antibody was more than anti-RNP antibody in patients with systemic lupus erythematosus by ID and IBT. The specificity of anti-SSA antibody was higher in IBT than that in ID. Conclusion： It will be more accurate and less missed diagnoses and diagnostic errors in systemic lupus erythematosus by combining ID and IBT.

关 键 词：系统性红斑狼疮 抗SSA 抗RNP 

分 类 号：R593.241[医药卫生—内科学]