甲状腺功能亢进症与妊娠  

Hyperthyroidism and pregnancy

作　　者：张闿珍[1,2] 

机构地区：[1]福建医科大学附属协和医院 [2]福建省内分泌研究所

出　　处：《国际内分泌代谢杂志》2009年第6期367-369,373,共4页International Journal of Endocrinology and Metabolism

摘　　要：本文研究甲状腺功能亢进症（甲亢）伴妊娠的安全性，无论是妊娠或哺乳，首选丙基硫氧嘧啶，也可用他巴唑；调整抗甲状腺药物（ATD）剂量，以游离T4为指标。甲亢患者应选择妊娠时机。妊娠早期病情会加重，ATD剂量需增加，晚期由于免疫耐受，甲亢可缓解，需减少剂量或停药，产后甲亢易复发。This paper discusses the safety of pregnancy in patients with hyperthyroidism. PTU or MMI is the first choice of them. And FT4 is the index to adjust the doses of anti-thyroid drug（ATD）. Patients with hyperthyroidism must choose the opportunity of pregnancy. Because the disease may be aggravated and need to increase the close of ATD in early stage, but it can alleviate and need to decrease or stop the ATD in late stage by immune resisting. Hyperthyroidism is easily relapsed after delivery.

关 键 词：甲状腺功能亢进症 妊娠 哺乳 丙基硫氧嘧啶 

分 类 号：R581.1[医药卫生—内分泌] R169.1[医药卫生—内科学]