重复经颅磁刺激对不完全性脊髓损伤患者的干预效果  

Effect of Repetitive Transcranial Magnetic Stimulation on Incomplete Spinal Cord Injury

作　　者：潘钰[1] 汪漩[2] 杜巨豹[1] 霍速[1] 周景升[1] 杨远滨[1] 屈亚萍[1] 刘霖[1] 朱琳[1] 宋为群[1] 王茂斌[1] 

机构地区：[1]首都医科大学宣武医院康复医学科,北京市100053 [2]首都医科大学生理学系,北京市100069

出　　处：《中国康复理论与实践》2009年第11期1058-1060,共3页Chinese Journal of Rehabilitation Theory and Practice

基　　金：首都医科大学基础与临床合作基金(2007JL12)

摘　　要：目的观察重复经颅磁刺激(rTMS)对不完全性脊髓损伤患者运动功能的影响。方法22例T5～T12节段脊髓损伤患者(ASCIC级)随机分为rTMS组和对照组。12例rTMS组患者于Cz部位给予磁刺激,并接受康复训练;10例对照组患者仅进行康复训练。治疗前后比较ASIA运动评分、轻触觉评分、针刺觉评分,抗重力体位双下肢主动关节活动度(ROM),脊髓损伤步行指数Ⅱ(WISCIⅡ)和功能独立性评定(FIM)。结果rTMS组和对照组患者治疗前临床评价指标均无显著性差异(P>0.05);两组治疗后ASIA运动评分、双下肢ROM、FIM评分均有改善(P<0.05);rTMS组治疗后WISCIⅡ也有改善(P<0.05),且ASIA运动评分高于对照组(P<0.05)。结论rTMS可促进不完全性脊髓损伤患者的运动功能改善,提高步行功能。Objective To investigate the effects of repetitive transcranial magnetic stimulation （rTMS） on motor recovery in patients with incomplete spinal cord injury （SCI）. Methods 22 patients with T5 - T12 incomplete spinal cord injury （ASIA C） were randomly divided into rTMS group and control group. 12 ptients in rTMS group were treated with 10Hz rTMS （10×5 s with 2 min interval） on motor cortex and rehabilitation. 10 patients in control group treated with rehabilitation only. They were assessed with ASIA motor score, ASIA pin prick score, ASIA light touch score, range of motion （ROM） of legs in antigravitation position, walking index for spinal cord injury Ⅱ （WISCI Ⅱ ） and functional independence measure （FIM） score before and 4 weeks after treatment. Results There was no difference between two groups with the clinical assessment before treatment （P〉 0.05）. The ASIA motor score, ROM of legs and FIM score improved in both groups after treatment （P〈0.05）. The score of WISCI Ⅱ also improved in rTMS group （P〈0.05）, and ASIA motor score improved more in rTMS group than that of control group （P〈0.05）. Conclusion rTMS can facilitate the recovery of the motor and walking function in patient with incomplete spinal cord injury.

关 键 词：脊髓损伤 重复经颅磁刺激(rTMS) 运动功能 康复 

分 类 号：R651.2[医药卫生—外科学]