滤白手工血小板的临床应用分析  

Analysis of clinical application of manual leukocyte-reduced platelets

作　　者：朱跃辉[1] 周立红[1] 王小平[1] 李莹[1] 钟阳青[1] 邵延芹[1] 冯莹[1] 

机构地区：[1]广州医学院第二附属医院输血科,广州510260

出　　处：《临床血液学杂志（输血与检验）》2009年第6期648-650,共3页Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)

摘　　要：目的:观察滤白手工血小板的临床输注效果,并就其与机采血小板进行比较,为临床如何选择滤白手工血小板和机采血小板提供依据。方法:统计我院2005-2008年临床血小板用量,了解手工血小板和机采血小板临床应用情况;通过对40例患者输用62次滤白手工血小板和67次机采血小板的比较,用血细胞计数仪分别计数血小板输注前后20～24h的数,根据输注后血小板校正增加指数(CCI)和血小板回收率(PPR),及临床出血症状有无改善进行疗效判断。统计2007年全年滤白手工血小板和机采血小板的输血反应率。结果:滤白手工血小板和机采血小板输注后的CCI和PPR值差异无统计学意义,滤白手工血小板和机采血小板的输注效果差异无统计学意义,滤白手工血小板和机采血小板输血反应率比较差异无统计学意义。结论:滤白手工血小板的应用能大量节约血资源,值得临床推广,滤白手工血小板和机采血小板在临床应用具同等价值。Objective：To observe the clinical infusion effect of manual leukocyte-reduced platelets, and compare with apheresis platelets , to provide the basis for clinical how to choose manual leukocyte-reduced platelets and apheresis platelets. Method：The amounts of clinical platelets in our hospital in 2005 --2008 were calculated to un derstand clinical application of manual platelets and apheresis platelets. 62 manual leukocyte reduced platelets and 67 apheresis platelets of 40 cases of patients were compared, corrected count increment （CCI）, percentage platelet recovery （PPR） and clinical symptoms of bleeding were used to appraise the clinical infusion effect;Transfusion reaction rate of the manual leukocyte-reduced platelets and apheresis platelets throughout the year 2007 were calculated. Result：The differences of CCI and PPR between manual leukocyte reduced platelets and apheresis platelets had no statistical significance. The difference of clinical infusion effect between manual leukocyte-reduced platelets and apheresis platelets was no statistical significance. The transfusion reaction rate of manual leukocyte reduced platelets and apheresis platelets was no statistical significant difference. Conclusion： The application of manual leukocyte-reduced platelets could save large blood resources and has the same value in clinical application as apheresis platelets, so it would be worthy to be popularized.

关 键 词：滤白 手工血小板 机采血小板 

分 类 号：R558[医药卫生—血液循环系统疾病]