生物共振技术对2282例变态反应性疾病变应原检测研究  

Research on allergen examination of allergic disease by bioresonance technology(2282 cases)

作　　者：张红[1] 张景龙[2] 熊亚茸[3] 郭小朝[4] 李淑婷[1] 

机构地区：[1]空军总医院皮肤科,北京100142 [2]北京市良乡医院皮肤科,北京102401 [3]空军总医院口腔科,北京100142 [4]空军航空医学研究所,北京100142

出　　处：《空军总医院学报》2009年第2期55-60,共6页Journal of General Hospital of Air Force,PLA

摘　　要：目的通过对2282例患者变应原检测,了解目前常见变应原与变态反应性疾病关系,并对其发病季节、年龄、性别及过敏反应强度等相关因素进行分析。方法采用生物共振技术行428种变应原检测。结果(1)变应原阳性检出率最高的前7种变态反应性疾病依次为:异位性皮炎(20/20,100%)、湿疹(366/390,93.8%)、过敏性鼻炎(53/57,93.0%)、过敏性皮炎(527/568,92.8%)、荨麻疹(532/617,86.2%)、过敏性紫癜(43/53,81.1%)、人工荨麻疹(29/43,67.4%)。阳性率差异非常显著(χ2=51.89,P<0.001)。荨麻疹、过敏性皮炎、湿疹、人工荨麻疹四类患者对食物类变应原反应强烈,过敏性鼻炎患者对吸入类、花粉类变应原反应强烈,异位性皮炎、过敏性紫癜患者对食物类变应原反应很强烈,差别非常显著(F(24,6252)=211.12,P<0.001)。(2)2282例患者变应原阳性率为2042例(89.48%),阳性率>5%的主要变应原有27种。7种顽固性变态反应性疾病中常见变应原33种,每种疾病主要变应原有所不同。当前主要变应原:贝类最高为占39.18%,其次虾39.08%、谷螨、粉螨31.00%、鱼类1:24.24%、尘螨21.35%、羊肉17.19%、鱼类2:12.19%、毛霉菌混合物10.92%、硫柳汞10.92%等。(3)男、女检测变应原阳性率(89.4%,89.7%)无统计学差异。7月阳性率最高,其次为2、5、8月。结论贝、虾、螨、鱼、羊肉、霉菌、硫柳汞等是当前北方地区主要变应原。夏秋季是过敏反应的高发季节。异位性皮炎变应原检出率最高,其次为湿疹、过敏性鼻炎、过敏性皮炎、荨麻疹、过敏性紫癜等;7种常见顽固性变态反应疾病主要变应原不同。Objective To realize the relation between allergen and diseases by examine the allergen of 2282 patients, to analyse the related factors such as season, age, sex and allergy strength. Methods Examine 428 kinds of allergen by bioresonance technology. Results （1） There are 7 kinds of diseases get the high positive rate. The positive rate of atopic dermatitis is 20/20（100%）, followed by eczema 366/390 （93.8%）, allergic rhinitis 53/57（93.0%）, allergic derma 527/568（92.8%）, urticaria 532 /617（86.2%）, henoch-schonlein purpura 43/53 （81. 1%）and artificial urticaria 29/43 （67.4%）. There were statistically significant differences in the positive rate of seven diseases（χ2=51.89, P〈0. 001）. Patients with urticaria, allergic derma, eczema and artificial urticaria have strong reaction for food related allergens. Patients with allergic rhinitis have strong reaction for Inhaled, like pollen allergens. Patients with atopic dermatitis have strong reaction for food related allergens. Patients with henoch-schonlein purpura have strong reaction for food related allergens. The difference was significant （F（24,6252）= 211. 12,P〈0. 001）. （2） Allergen testing positive rate is 89. 48% for 2042/2282 patients. There are 27 major allergens which allergens positive rate〉5%. There are 33 Common allergens for 7 kinds of stubborn allergic diseases. Different allergen for different diseases. The main allergen include： shellfish 39.18%, shrimp 39.08%, valley mite and powder mite 31.00%, fish1 24.24%, dust mite 21.35%, mutton 17.19%, fish2 12.19%, leaf mold 10.92%, merthiolate 10.92%. （3） The difference between allergy positive rate for men and women was not statistically significant（89.4% for men, 89.7% for women）. There was no significant difference be- tween age groups. The positive rate in July is the highest, followed by February, May and August. Conclusion shellfish, shrimp, valley mite and powder mite, fish, dust mite, mutton, leaf mold, and merthiolate are the main allergen in

关 键 词：核磁共振 生物分子/治疗应用 过敏反应 变应原 

分 类 号：R758.2[医药卫生—皮肤病学与性病学]