不同水平碘摄入量对甲状腺疾病的影响  

Effect of different uptake levels of iodine on thyroid diseases

作　　者：肖天梅[1] 李乐愚[1] 林泽宏[1] 

机构地区：[1]广州中医药大学中山附属医院内分泌科,广东中山528400

出　　处：《临床医学》2009年第12期23-24,共2页Clinical Medicine

摘　　要：目的了解不同水平碘摄入量与甲状腺疾病的关系,探讨个体化补碘的依据及临床意义。方法测定甲状腺疾病组和正常对照组的甲状腺功能、甲状腺过氧化物酶抗体(TPOAb)、甲状腺球蛋白抗体(TGAb)、甲状腺彩色多普勒及尿碘,比较不同疾病组患者尿碘水平。结果甲状腺功能异常、甲状腺肿及甲状腺结节患者的尿碘中位数显著高于正常对照组(P<0.01),且随尿碘水平的增加,甲状腺功能亢进症患者的初治期延长。结论碘过量会增加甲状腺疾病的发生率,尿碘测定有助于指导个体化补碘。Objective To investigate the relationship of different intake level of iodine and thyroid diseases, and to discuss the scientific evidences and meanings of individual iodine supplement. Methods The thyroid hormones include FT3 , FT4,TSH, TPOAb, TGAb, thyroids B ultrasound and urinary iodine were measured. Urinary iodine levels were compared between different thyroid disease and normal control group. Results The urinary iodine median was higher in different thyroid disease including thyroid disfunction, goiter and thyroid nodal disease than that in normal control group with a statistical difference（ P 〈 0.01 ）. With higher of urinary iodine in hyperthyroidism patients, the primary treatment period was proved longer. Conclusion Increased intake of iodine increases the incidence of thyroid diseases, the measurement of urinary iodine level may guide iodine intake in individual.

关 键 词：甲状腺疾病 尿碘 相关性 

分 类 号：R581[医药卫生—内分泌] R591.1[医药卫生—内科学]