慢性肾炎患者肝肾阴虚证与血清中微量元素关系研究  

Study on Relation of Trace Elements with Glomerular Nephritis with Syndrome of Hepatic and Renal Yin Deficiency

作　　者：英锡相[1] 赵友林[2] 何学红[2] 马进[2] 李伟[3] 

机构地区：[1]辽宁中医药大学药学院,辽宁大连116600 [2]辽宁中医药大学附属医院,辽宁沈阳110032 [3]辽宁中医药大学基础医学院,辽宁沈阳110032

出　　处：《辽宁中医药大学学报》2009年第12期42-43,共2页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：辽宁省自然科学基金项目(20072073)

摘　　要：目的:初步探讨慢性肾炎肝肾阴虚证与血清微量元素关系。方法:快速电感耦合等离子体质谱(ICP-MS),同时测定血清中多种微量元素。样品加5mL浓硝酸经微波消化系统消解后可直接分析。结果:在慢性肾炎肝肾阴虚证等患者血清微量元素与正常组比较,Zn、Fe、Cu明显低于正常值(P<0.05),Mn元素高于正常组(P<0.05)。结论:实验结果表明慢性肾炎肝肾阴虚证患者血清中微量元素发生改变,将为临床慢性肾炎肝肾阴虚证研究提供借鉴。Objective： Study on the trace element relationship of glomerular nephritis with hepatic and renal yin deficiency. Methods： A rapid inductively coupled plasma mass spectrometry （ICP-MS） was developed to simultaneously determine many trace elements in blood serum samples. Samples were analyzed directly following an acid digestion with 5mL of cone. HNO3 by the microwave digestion system. Results： Zn, Fe, Cu trace elements of glomerular nephritis with hepatic and renal yin deficiency were lower than that of normal group （P〈0.05）, conversely, Mn was higher. Conclusion： The experiment can be as the indication to differentiation of symptoms and signs for classification of syndrome based on the element change of glomerular nephritis with hepatic and renal yin deficiency.

关 键 词：慢性肾炎 肝肾阴虚证 微量元素 电感耦合等离子体质谱 

分 类 号：R692.3[医药卫生—泌尿科学]