胆舒颗粒的主要药效学研究  

Study on the main pharmacodynamics of Danshu granule

作　　者：李矗[1] 王珍[2] 

机构地区：[1]安徽医科大学附属安徽省立医院,230001 [2]安徽省药品审评认证中心

出　　处：《中国医学创新》2009年第35期12-14,共3页Medical Innovation of China

摘　　要：目的研究胆舒颗粒的主要药效作用。方法采用胆固醇诱导家兔胆结石模型、手术引流家兔胆汁流量、新斯的明致家免胆总管Oddi括约肌痉挛模型分别观察胆舒颗粒抗胆结石形成、利胆、解痉作用。结果胆舒颗粒可防治胆结石形成,促进胆汁引流,缓解Oddi括约肌痉挛。结论胆舒颗粒对胆道感染合并结石有一定的防治作用。Objective To study the main pharmacodynamics of Danshu granule. Methods By using rabbit model of cholelithiasis induced by cholesterol, the rabbits＇ bile flow rate by surgical drainage, spasm of the rabbits＇ cholodoch oddi sphincter caused by administering neostigmine, we studied the effects of Danshu granule on the prophylaxis of eholelithiasis, cholagogic action and spasmolysis. Results Danshu granule was effective on preventing and treating cholelithiasis, promoting the rabbits＇ bile flow rate, relieving the spasm of eholedoch oddi sphincter. Conclusion Danshu granule can be used to prevent and treat biliary tract infection complicated with cholelithiasis.

关 键 词：胆舒颗粒 利胆 药效学 

分 类 号：R285.5[医药卫生—中药学]