鹅副粘病毒病的研究  

A PRIMARY STUDY ON THE GEESE'S PARAMYXOVIRUS INFECTIONS

作　　者：王永坤[1] 田慧芳[1] 周继宏[1] 严维巍[1] 钱忠明 许益民[1] 朱国强[1] 周明荣 庄国宏[1] 陆杏梅 叶斌 卞汝霖 

机构地区：[1]江苏农学院动物医学系,扬州225009 [2]江都市兽医站 [3]扬州市兽医站

出　　处：《福建畜牧兽医》1998年第4期1-3,共3页Fujian Journal of Animal Husbandry and Veterinary medicine

摘　　要：用SPF鸡胚分别从扬州、苏州、盐城等市不同患病鹅群的病鹅肝、脾等病料分离到7株病毒。鸡胚分离的病毒株均具有凝集鸡红细胞．HA为27-14．并被康复血清所抑制。毒价ELD50为1011、24，人工感染易感鹅引起发病死亡，并出现与自然病例相同的症状和病变：三株鸡胚绒尿液毒作负集电镜观察，病毒颗粒均呈大小不一，形态不正．表面有密集纤突结构，病毒内部由囊膜包裹着的螺旋对称的核衣壳．大小平均直径为120nm。根据血清学检测、病毒形态结构以及特性等初步的研究结果，本病分离毒株为副枯病毒科、副粘病毒属一员。应用分离毒株研制的灭活苗对鹅有良好的保护率。A new viral disease of geese was reported, seven strains of virus were isolated from different infected geese's livers and spleens from Yangzhou using SPF embryos. All of them can agglutinate chicken,s red blood cells and the haemaglutination activity can be inhibited by the convalescent antiserum. The maxium HA titer reached 27-14. and the ELD50 is 1011.24 per millited. Artificial infection can cause lethal infection among geese which has the asme patholgoic changes and symptoms as the natural case. Tile virus fluids by chicken embryos from three strains of vinous were pleomorphism, 120urn in diameter. and enveloped with lots of projections on the particles surface, belieal nucleocapsid in negative staining preparation. This virus was i'lclltificd as paramyxoviridae, paramyxoviurs by serologic tests and morphological examination. The inactived vaccine made from isolated virus could give good protection against infection.

关 键 词：鹅 副粘病毒 病毒形态 疫苗 

分 类 号：S858.33[农业科学—临床兽医学]