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机构地区:[1]山东大学公共卫生学院卫生检验研究所,济南250012
出 处:《中国公共卫生》2009年第12期1451-1452,共2页Chinese Journal of Public Health
基 金:山东省自然科学基金(Y2007C086)
摘 要:目的探讨手机辐射对孕鼠和胎鼠脑组织的损伤作用。方法孕鼠经不同强度手机辐射后,测定孕鼠及胎鼠脑组织中超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)、丙二醛(MDA)含量。结果与对照组比较,孕鼠脑组织中SOD、GSH-Px、MDA含量在各组间差异均无统计学意义(P>0.05)。辐射组子代脑组织中SOD活力(U/mg.prot)下降,其中高强度组(38.56±4.62)、中强度组(40.05±4.74)与对照组(43.53±5.38)比较,差异有统计学意义(P<0.05);GSH-Px水平(U/mg.prot)下降,其中高强度组(33.80±6.29)、中强度组(35.03±7.18)与对照组(40.58±8.03)比较,差异有统计学意义(P<0.05);MDA含量(nmol/mg.prot)升高,其中高强度组(4.09±0.68)、中强度组(3.95±0.64)与对照组(2.89±0.57)比较,差异有统计学意义(P<0.05);但低强度组的SOD活力(42.79±5.06)、GSH-Px水平(39.95±9.02)和MDA含量(3.05±0.76)与对照组比较差异无统计学意义(P>0.05)。结论孕鼠在孕期中接受手机电磁辐射达一定时间,会对子代脑组织的抗氧化系统产生一定的损害。Objective To investigate the effect of electromagnetic radiation of cellular phone on of brain tissue of pregnant and fetal rats.Methods Pregnant rats were radiated with various levels of electromagnetic radiation and then the contents of superoxide dismutase(SOD),glutathione peroxidase(GSH-Px)and malondialdehyde(MDA) in pregnant and fetal rats' brain tissue were tested.Results No significant difference was found in pregnant rat brain tissue among the four groups.In rats' brain tissue,the content of SOD(U/mg prot) decreased after irradiation with significant differences among the high intensity group(38.56±4.62),middle intensity group(40.05±4.74) and control group(43.53±5.38,P〈0.05).The content of GSH-Px(U/mg prot) decreased after irradiation,and the differences were significant among the three groups(33.80±6.29,35.03±7.18,40.58±8.03,respectively,P〈0.05).The content of MDA(nmol/mg prot) increased after irradiation,and the differences were also significant among the three groups(4.09±0.68,3.95±0.64,2.89±0.57,respectively,P〈0.05).There was no significant difference between low intensity group and control group in the content of SOD(42.79±5.06),GSH-Px(39.95±9.02) and MDA(3.05±0.76,P〉0.05).Conclusion Receiving certain intensity of electromagnetic radiation from cell phone during pregnancy has certain harm effect on antioxidant system of offspring's brain tissue in rats.
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