振动觉阈值测定在糖尿病周围神经病变早期诊断中的临床应用  

Clinical application of vibration perception thresholds tests for the early diagnosis of diabetic peripheral neuropathy

作　　者：陶文玉[1] 张瑛[1] 孙川竹 徐凡[1] 

机构地区：[1]云南省第二人民医院内分泌科,云南昆明650021

出　　处：《中国现代医学杂志》2009年第21期3290-3292,共3页China Journal of Modern Medicine

摘　　要：目的探讨振动觉阈值(VPT)测定在糖尿病周围神经病变(DPN)早期诊断中的临床应用。方法符合入选标准的287例2型糖尿病患者中,比较有神经症状/体征组(151/287,组1)和无神经症状/体征组(136/287,组2)的VPT测定结果。结果287例患者VPT总异常率81.18%(233/287);组1的VPT总异常率94.70%(143/151),其中轻中度异常率56.29%、重度异常率38.41%;组2的VPT总异常率66.18%(90/136),其中轻中度异常率52.21%、重度异常率13.97%。两组比较在总异常率和重度异常率上均差异有显著性(P<0.01和P<0.05)。结论VPT测定方便,能敏感地对糖尿病周围神经病变做出早期诊断。[ Objective ] To explore the early diagnostic value of vibration perception thresholds tests （VPT） in diabetes with peripheral neuropathy （DPN）. [Methods] The VPT tests were examined in 287 diabetic patients and their results were compared in two groups, which were divided for having or not having the symptoms/signs of peripheral neurepathy. [Results] The total abnormal ratio of VPT in 287 cases was 81.18% （233/287）. The abnormal ratio of VPT in the group with symptoms/signs of neuropathy （G1） was 94.70% （143/151） and that of VPT in the group without symptoms/signs of neuropathy （G2） was 66.18% （90/136）. There was a significant difference between two groups （P 〈0.01）. [ Conclusion] The VPT detection is convenient and sensitive for DPN screening earlier.

关 键 词：振动觉阈值测定 糖尿病周围神经病变 

分 类 号：R587.2[医药卫生—内分泌] R44[医药卫生—内科学]