Hypereosinophilia with a giant thrombus in the right ventricle： Loffler endocarditis in an ll-year-old girl  

作　　者：GUO Yong-fang HAN Zhi-hong JIANG Teng-yong FANG Wei DONG Ran WU Xue-si 

机构地区：[1]Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China [2]Department of Pathology , Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China [3]Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

出　　处：《Chinese Medical Journal》2009年第23期2914-2916,共3页中华医学杂志（英文版）

摘　　要：Hypereosinophilic syndrome （HES） is a rare disorder that can be seen in various organ systems, but its major tissue target is the heart.＇ The most characteristic cardiovascular abnormality in HES is endomyocardial fibrosis, initially described in 1936 by Loffler, who called it ＂fibroplastic parietal endocarditis with blood eosinophilia.＂ The overall prognosis of patients with Loffler endocarditis is very poor. Current treatments include anticoagulation and anti-eosinophils therapy, and surgery only has been used in selected cases.Hypereosinophilic syndrome （HES） is a rare disorder that can be seen in various organ systems, but its major tissue target is the heart.＇ The most characteristic cardiovascular abnormality in HES is endomyocardial fibrosis, initially described in 1936 by Loffler, who called it ＂fibroplastic parietal endocarditis with blood eosinophilia.＂ The overall prognosis of patients with Loffler endocarditis is very poor. Current treatments include anticoagulation and anti-eosinophils therapy, and surgery only has been used in selected cases.

关 键 词：hypereosinophilic syndrome Loffler endocarditis ADOLESCENT 

分 类 号：Q463[生物学—生理学] Q592.1