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机构地区:[1]北京医科大学
出 处:《中国工业医学杂志》1998年第6期334-336,共3页Chinese Journal of Industrial Medicine
基 金:国家自然科学基金
摘 要:目的寻找简便方法来观察动物接噪的个体差异。方法按大鼠接噪〔100dB(A)〕0.5h血压和心率的变化,将大鼠分为A、B两类,再观察接噪〔105dB(A)〕15周内各类大鼠血压动态变化。结果A类反应大鼠接噪8周后,血压明显高于B类反应大鼠暴露组,12,15周时血压明显高于A类反应大鼠对照组,而B类反应大鼠在同样条件下未见血压明显变化。结论此分型方法比原来用心电图分型方法简单,更便于观察现场接噪工人的个体差异。Objective To search a simple way for identifying the individual sensitivity due to noise.Method The rats were divided into type A and type B according to their responses in blood pressure(BP) and heart rate (HR) after 0 5h noise exposure at 100 dB(A).Result It was showed that the responsibility of BP to noise in type A rats was greater than that of rats in type B.In type A,BP increased significantly after 8 week of noise exposure,compared to rats in type B under the same condition.After 12 and 15 week noise exposure,BP of exposed rats in type A was higher than that of the control group in type A,BP of rats in type B still remained unchanged during the exposure compared to the controls.Conclusion The new method seems more simple than that of the original method with electrocardiography in study the individual difference of the sensitivity to noise.
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