甲磺酸罗哌卡因和盐酸罗哌卡因肌间沟臂丛神经阻滞的比较  

Comparison of the efficacy of ultrasound guided interscalene brachial plexus block with 0.5% ropivacaine hydrochloride and 0.596% ropivacaine mesylate

作　　者：顾晨桃[1] 王爱忠[1] 江伟[1] 

机构地区：[1]上海交通大学附属上海第六人民医院麻醉科,200233

出　　处：《临床麻醉学杂志》2009年第11期940-942,共3页Journal of Clinical Anesthesiology

摘　　要：目的观察0.596%甲磺酸罗哌卡因和0.5%盐酸罗哌卡因在超声引导下行肌间沟臂丛神经阻滞的效果。方法60例上肢手术行肌间沟臂丛麻醉的患者,随机均分成两组:A组给予0.596%甲磺酸罗哌卡因30 ml;B组给予0.5%盐酸罗哌卡因30 ml。比较两组感觉及运动阻滞起效时间、阻滞程度、运动恢复时间、镇痛持续时间和不良反应。结果A组尺神经感觉阻滞起效时间显著快于B组[(38.30±14.65)min vs.(48.03±22.34)min](P<0.05)。注药60 min A组尺神经感觉完全阻滞29例(96.7%),显著多于B组的20例(66.7%)(P<0.05)。结论0.596%甲磺酸罗哌卡因的尺神经感觉阻滞优于0.5%盐酸罗哌卡因。Objective To compare the efficacy of ultrasound guided interscalene brachial plexus block（IBPB） with 0.5% ropivacaine hydrochloride and with 0. 596% ropivacaine mesylate. Methods Sixty patients under interscalene brachial plexus anesthesia for upper limb operation, were randomly assigned to group A received 0. 596% ropivacaine mesylate 30 ml and group B received 0. 5% ropivacaine hydrochloride 30 ml with 30 cases each. The efficacy of IBPB was recorded. Results The onset time of ulnar nerve sensory block in group A was significantly shorter than that in group B [（38.30±14. 65） min vs. （48. 03±22.34） min]（P〈0.05）. The percentage of complete ulner nerve sensory block within 60 min in group A was 96.7%（29/30） ,which was higher than 66.7%（20/30） in group B（P〈0. 05）. Conclusion Ultrasound guided IBPB with 0. 596% ropivaeaine mesylate has better ulnar nerve sensory blockade than that with 0.5% ropivacaine hydrochloride.

关 键 词：超声引导 肌间沟臂丛神经阻滞 甲磺酸罗哌卡因 盐酸罗哌卡因 

分 类 号：R614[医药卫生—麻醉学]