羊水栓塞导致孕产妇死亡的病理诊断和预防  

Pathologic diagnosis and prevention of maternal deaths induced by amniotic fluid embolism

作　　者：初松涛[1] 刘卯阳[1] 李洪涛[1] 

机构地区：[1]北华大学基础医学院法医教研室,吉林吉林132000

出　　处：《中国妇幼保健》2009年第35期4964-4966,共3页Maternal and Child Health Care of China

摘　　要：目的:探讨羊水栓塞致孕产妇死亡的病理诊断和羊水栓塞的预防措施,用于提高临床诊断率,减少误诊率,增加病理诊断率,降低临床上羊水栓塞的发生率。方法:研究18例较典型的因羊水栓塞致死的案例,通过完整的尸体解剖检查,结合临床资料及相关文献资料,分析羊水栓塞的发病诱因及猝死机制、临床表现及诊断、病理表现和预防措施。结果:死者肺组织切片内均可见肺羊水栓塞的特征性病理改变,18例尸检明确病理诊断为羊水栓塞。结论:羊水栓塞的正确病理诊断需结合临床症状、实验室检查及尸体解剖检查等多方面结果综合分析判断,羊水栓塞的预防措施是针对所发现的羊水栓塞有关诱因加以防范。Objective： To explore the pathologic diagnosis and preventive measures of maternal deaths induced by amniotic fluid embolism, increase clinical diagnostic rate and pathologic diagnostic rate, reduce misdiagnosis rate and incidence of amniotic fluid embolism. Methods： 18 typical maternal deaths induced by amniotic fluid embolism were analysed, by means of a complete autopsy examination combined with clinical data and relevant literature, predisposing factors and pathogenesis of sudden death, clinical manifestations, diagnosis, pathological manifestations and preventive measures were analysed. Results ： Characteristic pathological changes of pulmonary amniotic fluid embolism were detected in lung tissue slices of maternal deaths. Pathological diagnosis of 18 maternal deaths was amniotic fluid embolism by means of autopsy. Conclusion： The correct pathologic diagnosis of amniotic fluid embolism requires a combination of clinical symptoms, laboratory examination and postmortem examination results, preventive measures of amniotic fluid embolism are based on related predisposing factors.

关 键 词：羊水栓塞 猝死 病理诊断 预防 

分 类 号：R714.468[医药卫生—妇产科学]