肠腑康胶囊A提取工艺的研究  

Optimization of Extraction Technique of Changfukang A Capsule

作　　者：蒙麦侠[1] 杨智峰[1] 杨瑞瑞 郑洁[1] 

机构地区：[1]陕西省中医药研究院,陕西西安710013 [2]陕西省食品药品监督检验所,陕西西安710061

出　　处：《中国中医药信息杂志》2009年第12期54-55,共2页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：陕西省科学技术厅攻关项目[2006k16-G13(5)]

摘　　要：目的优选肠腑康胶囊A的提取工艺。方法建立高效液相色谱法测定橙皮苷含量的方法，以干膏率、橙皮苷含量为考察指标，采用L9（3^4）正交试验优选提取工艺。结果最佳提取工艺为加8倍量水，回流提取3次，每次1．5h。结论优化的提取工艺稳定、可行。Objective To optimize the extraction technique of Changfukang A capsule. Methods A RP-HPLC method for Hesperidin was established. With the water extraction rate and Hesperidin as the parameters, the extract condition of Changfukang A capsule was optimized by orthogonal design. Results The optimized extraction technique was as follows： The medicinal material was extracted for 3 times with total 8 times of water, 1.5 hours for each time. Conclusion The optimal preparation prosess was validated to be stable and feasible.

关 键 词：肠腑康胶囊A 正交试验 高效液相色谱法 干膏率 橙皮苷 

分 类 号：R283.5[医药卫生—中药学]