类风湿性关节炎血浆置换治疗前后微量元素铜铁锌的变化  

Changes of Copper, Zinc and Iron in Rheumatoid Arthritis Caused by Plasma Exchange

作　　者：张红[1] 申红[1] 肖东杰[1] 孙善会[1] 孙红胜[1] 潘广锦[1] 

机构地区：[1]济南市中心医院,济南250013

出　　处：《广东微量元素科学》1998年第7期47-50,共4页Trace Elements Science

摘　　要：采用原子吸收分光光度计，对15例类风湿性关节炎患者血浆中铜、铁、锌的含量进行测定，并与正常对照组作比较。结果显示患者铜明显升高，锌降低，铜／锌比值升高。血浆置换后铜含量及铜／锌比值恢复正常，锌含量有所恢复。证明类风湿性关节炎患者铜、铁、锌的代谢方面存在一定缺陷。血浆置换可纠正这种微量元素代谢异常，从而起到改善免疫功能的作用。The concentrations of zinc, copper and iron in 15 patients with RA were measured by atomicabsorption spectrmetry (AAS) and were compared with normal controls. The result showed that in RA casesthe plasma concentration of zinc was significantly lower, while the concentration of copper and the ratio ofcopper/zinc were significantly higher than those in normal controls. After plasma exchange, the centration of copper and the ratio of Cu/Zn recovered to nounal, and the concentration of zinc also recovered.This suggested that there are some defects in copper, zinc and iron metabolism. Plasma exchange can improve the metabolism.

关 键 词：类风湿性关节炎 血浆置换 铜 铁 治疗 微量元素 

分 类 号：R593.22[医药卫生—内科学]