^(18)F-FDG PET/CT显像在恶性黑色素瘤诊断及分期中的价值  

Clinical value of ^(18)F-FDG PET/CT in diagnosis and staging of malignant melanoma

作　　者：李丽琴[1] 李德鹏[1] 王争明[1] 龙凤[1] 

机构地区：[1]中国人民解放军第二炮兵总医院肿瘤放射诊疗中心,北京100086

出　　处：《中国医学影像技术》2009年第11期2106-2109,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨恶性黑色素瘤的全身18F-FDG PET/CT影像表现特点,评价18F-FDG PET/CT对恶性黑色素瘤分期的价值。方法对28例病理证实的恶性黑色素瘤患者的18F-FDG PET/CT全身显像资料及临床资料进行回顾性分析。结果眼球内黑色素瘤表现为眼球内高密度结节,>1.0cm病灶FDG代谢增高,PET/CT较单独PET或单独CT发现更多转移灶,但对于原发病灶的显示较MRI差。颅内恶性黑色素瘤PET/CT表现有一定特征,但对病灶的检出及鉴别诊断较MRI差。四肢恶性黑色素瘤原发灶显示为局部软组织肿胀,FDG摄取未见明显增高;转移灶显示为局域淋巴结转移及远处转移,单独CT对所有检出病灶诊断的阳性率为87.20%,单独PET对所有检查病灶诊断的阳性率为72.5%,PET-CT对所有检查病灶诊断的阳性率为99.1%。结论18F-FDG PET/CT对于恶性黑色素瘤的定性诊断有一定价值,对判断临床分期具有重要价值。PET-CT检查较单独CT或单独PET检查能够检出更多病灶,提高诊断阳性率。Objective To discuss the ^18 F-FDG PET/CT features of melanoma,and to evaluate its value in staging of melanoma.Methods ^18 F-FDG PET/CT images and clinical data of 28 patients with melanoma proved pathologically were retrospectively analyzed.Results Lesions of choroidal melanoma in the eyes presented with hyperdensity,and metabolism increased in 〉1.0 cm lesions.PET/CT found more lesions than PET or CT,but inferior to MRI in displaying primary lesions.Intracranial melanoma had some characteristics on PET/CT,but MRI was better than PET/CT in detecting and differentiating these lesions.Local edema in soft tissues without uptake of ^18 F-FDG appeared in primary melanoma in the extremities.Local and remote metastasis could be found in whole body using ^18 F-FDG PET/CT.The frequency of privately CT and privately PET were 87.20% and 72.50%.Conclusion ^18 F-FDG PET/CT has some value in diagnosis and staging of melanoma.

关 键 词：黑色素瘤 体层摄影术 发射型计算机 X线计算机 诊断 肿瘤分期 

分 类 号：R814.42[医药卫生—影像医学与核医学] R739.5[医药卫生—放射医学]