磷酸改性的Hβ分子筛催化合成对甲氧基苯乙酮  

Synthesis of p-Methoxyacetophenone Catalyzed by Phosphoric Acid Modified Hβ Zeolite

作　　者：白国义[1] 窦海洋[1] 樊欣欣[1] 王海龙[1] 牛立博[1] 

机构地区：[1]河北大学化学与环境科学学院,河北保定071002

出　　处：《精细化工》2009年第12期1192-1195,共4页Fine Chemicals

基　　金：国家自然科学基金资助项目(20806018);河北省自然科学基金资助项目(B2007000156);河北省教育厅自然科学研究重点计划资助项目(ZD200910)~~

摘　　要：在磷酸改性的Hβ分子筛催化剂作用下,以苯甲醚和乙酸酐为原料,通过Friedel-Crafts酰基化反应合成了对甲氧基苯乙酮。通过XRD和NH3-TPD表征研究了磷酸的改性作用。系统地考察了反应温度、催化剂用量和反应时间对乙酸酐转化率的影响,确定了最佳反应条件:反应温度120℃、催化剂用量2.0g、反应时间2h。在催化剂的4次套用实验中,乙酸酐的转化率和对甲氧基苯乙酮的选择性均大于99.0%。p-Methoxyacetophenone was synthesized by the Friedel-Crafts acylation of anisole and acetic anhydride over the phosphoric acid modified Hβ zeolite. The effect of phosphoric acid modification was investigated based on XRD and NH3-TPD characterization. The influences of the reaction temperature, the catalyst amount and the reaction time on the acetic anhydride conversion were investigated and optimized. The conversion of acetic anhydride and the selectivity to p-methoxyacetophenone are both higher than 99.0% in four runs catalyzed by the recycled catalysts under the optimum reaction conditions,while the reaction temperature is 120 ℃, the catalyst amount is 2.0 g and the reaction time is2 h.

关 键 词：酰基化 HΒ分子筛 磷酸改性 对甲氧基苯乙酮 催化与分离提纯技术 

分 类 号：O643.322[理学—物理化学]