医用钛合金表面改性的研究进展  

Progress in Surface Modification of Titanium Alloys for Biomedical Applications

作　　者：曹辉亮[1] 刘宣勇[1] 丁传贤[1] 

机构地区：[1]中国科学院上海硅酸盐研究所,上海200050

出　　处：《中国材料进展》2009年第9期9-17,共9页Materials China

基　　金：国家973重点基础研究发展规划项目(2005CB623901);国家自然科学基金项目(30700170);上海市纳米专项(0852nm03300)

摘　　要：从金属植入体与生物环境的界面反应,以及钛植入体表面现阶段存在的主要问题出发,叙述了近年来钛表面生物活性、生物相容性、血液相容性、抗菌性涂层的制备、结构及性能,重点总结了应用等离子体喷涂技术制备羟基磷灰石涂层、硅酸盐陶瓷涂层、纳米ZrO2涂层、纳米TiO2涂层,以及采用等离子体浸没离子注入/沉积技术对钛合金表面进行离子注入和薄膜沉积的研究结果。最后,基于钛硬组织植入体表面需求,指出钛硬组织植入体表面改性设计与制备应注重改性层的综合生物学性能及力学安全性。Fabrication, microstructure and properties of the films/coatings deposited on biomedical titanium alloys for improving their bioactivity, biocompatibility, hemocompatiblity and antibacterial properties, were reviewed from the view of reactions between the titanium alloy implant and the biological environment, as well as the drawbacks of the conventional implant surfaces. Special attentions were drawn on the results of plasma spraying hydroxylapatite, silicate, nano ZrO2 and TiO2 coatings, and plasma immersion ion implantation/deposition on titanium alloys. In addition, the design and fabrication of titanium surfaces with multi-biological functions and enhanced mechanical properties were prospected based on the requirements of hard tissue replacement.

关 键 词：钛合金 生物材料 表面改性 植入体 

分 类 号：TG146.23[一般工业技术—材料科学与工程]