流动注射化学发光法测定多巴胺  

DETERMINATION OF DOPAMINE BY FLOW INJECTION ANALYSISWITH CHEMILUMINESCENCE DETECTION

作　　者：李丽清[1,2,3] 孟兆珂[1,2,3] 吕九如[1,2,3] 

机构地区：[1]泰安师范专科学校化学系 [2]泰安市肿瘤医院 [3]陕西师范大学化学系

出　　处：《泰山医学院学报》1998年第2期115-117,共3页Journal of Taishan Medical College

基　　金：国家自然科学基金

摘　　要：目的建立化学发光测定多巴胺新方法。方法采用流动注射技术，研究了多巴胺———高锰酸钾体系的化学发光行为。结果方法的检出限为６×１０９ｇ／ｍｌ，线性范围为２０×１０８～８０×１０５ｇ／ｍｌ。对４０×１０７ｇ／ｍｌ多巴胺进行１１次平行测定，相对标准偏差为１８％。结论该方法用于药剂中多巴胺含量测定，结果与药典标准方法测得值一致。Objective To establish a new chemiluminescence method of determinating dopamine. Methods: The flow injection technique was used, and the chemilumines cence reaction of dopamine-KMnO4 was studied. Results Detection limit was 6×109g/ml. The linear range was 2.0×108～8.0×105g/ml. The parallel determination was done 11 times to 4.0×109g/ml dopamine and the relative standard deviation was 1.8%. Conclusion Chmiluminescence with flow injection is in accordance with standard method in the determination of dopamine.

关 键 词：多巴胺 化学发光 流动注射 

分 类 号：R971.93[医药卫生—药品]