长骨液促进骨延长区骨矿化的实验研究  

Experimental Study of the Effect of Zhang Gu Ye on Promotion of Bone Mineralizatin in Bone Lengthening Region

作　　者：邹培[1] 阮默[1] 李主一[1] 李峻辉[1] 翁龙江[1] 周中英[1] 林月秋[1] 孔媛 李光全[1] 靳杭红[1] 

机构地区：[1]成都军区昆明总医院全军骨科中心,昆明650032

出　　处：《中国骨伤》1998年第5期15-17,共3页China Journal of Orthopaedics and Traumatology

摘　　要：目的　观察中药长骨液对骨延长区骨矿化的影响。方法　山羊１２只，于胫骨上干骺端做成骨延长模型，分成对照组和中药治疗组，进行实验，观察延长区成骨情况。结果内服长骨液组骨 延长区Ｘ线平片平均光密度值、骨密度、以及新骨组织钙含量、灰密度、四环素荧光双标间距等指标 均明显高于对照组（Ｐ＜０．０５）。结论中药长骨液具有明显加速骨延长区骨矿化的作用。Aim To observe the effect of Chinese medicine Zhang Gu Ye (ZGY) (Bone Growthing Fluid) on bone mineralization in bone lengthening region. Methods Twelve goats were used to make bone lengthening model in the upper metaphysis of tibia, and then divided into control group and ZGY treated group to examine bone growth in the distracted area. Results In ZGY group, the optical density of X--ray film, and the bone density,calcium content and ash density of new bone,and the distance between two fluorescent lines of incorporated tetracycline were significantly increased as compared with those in control group (P＜0.05). Conclusion The Chinese medicine, ZGY can obviously play a role in accelerating the bone mineralization in the distracted area.

关 键 词：长骨液 骨增长 中药 骨矿化 药理 

分 类 号：R285.5[医药卫生—中药学]