利多卡因静脉注射在预防气管插管应激反应中的临床观察  

Observing the prevention of intubation reaction with Lidiocain

作　　者：李淑芬[1] 孟杰[1] 

机构地区：[1]湖北省孝感市中心医院麻醉科,湖北孝感432000

出　　处：《中国当代医药》2009年第23期78-79,共2页China Modern Medicine

摘　　要：目的:观察利多卡因预防气管插管反应的有效性。方法:ASAⅠ～Ⅲ级患者40例,随机分为两组,Ⅰ组插管前预注生理盐水5ml,Ⅱ组插管前1min静注利多卡因1mg/kg。监测各时段血流动力学指标,并记录两组患者插管后出现呛咳的例数。结果:与麻醉前比较,两组插管前SBP、DBP、HR均明显下降(P<0.05),组间比较无明显差异;与Ⅱ组比较,Ⅰ组插管后血压、心率均明显升高,并有部分患者出现呛咳,需加深麻醉,组间比较,差异有统计学意义(P<0.05)。结论:静注利多卡因可有效预防气管插管反应。Objective：To observe the effect of lidiocain on preventing trachea intubation reaction. Methods ：40 cases with ASA Ⅰ-Ⅲ were randomly divided into two groups. Group Ⅰ was given 0.9 % natri chloride 5 ml and group Ⅱ was given 2% lidocain 1 mg/kg in venus Ⅰ minute before trachea intubation. Then detected several significance of the blood fluence at every time and how many patients coughing in two groups. Results ：After inducing SBP, DBP, HR were all decreased obviously （P〈0.05）, There was no significant difference between the two groups（P〈0.05）. While, there was significant diffenence of SBP, DBP,HR in group I and several patients cough after trachea intubation. Conclusion：2% lidiocain in venus is effective in preventirg intubation reaction.

关 键 词：利多卡因 气管插管 插管反应 

分 类 号：R614.24[医药卫生—麻醉学]