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机构地区:[1]北京工业大学生命科学与生物工程学院,北京100124
出 处:《北京生物医学工程》2009年第6期569-572,共4页Beijing Biomedical Engineering
基 金:国家自然科学基金(10772010);北京市自然科学基金(3062003;3092004)资助
摘 要:目的探讨搭桥术对主动脉夹层假腔内血流动力学参数的影响及该术式的治疗有效性。方法利用AutoCAD软件构建DeBakeyⅢ型主动脉夹层及其移植管搭桥术的理想化二维几何模型,然后利用ANSYS软件进行数值模拟,分析计算结果的血流动力学特性。结果在实施搭桥手术后,假腔内的血流速度与压力均小于实施搭桥手术前的值。结论利用旁路搭桥转流术可有效地降低主动脉弓的血压,减轻血流对夹层病变的冲击和压力。由此推之到其对防止夹层破裂,促进夹层局部病变愈合,是一种有效的手术方式。Objective To investigate the influence of bypassing operation on the hemodynamics parameters of aortic dissection and the feasibility of this therapeutic approach in clinical application. Methods Idealized two-dimensional geometry models of DeBakey Ⅲ aortic dissection and its bypassing treatment were constructed with the software of AutoCAD. Then, these two models' numerical stimulations were performed utilizing the software of ANSYS, and the hemodynamics results were analyzed. Results After bypassing operation, the blood flow velocity and the pressure in the false lumen of aortic dissection were both less than those before the operation. Conclusion Bypassing effectively reduced the pressure in aortic arch and eased the impulsion and stress of blood flow on the pathological dissection. It was supposed that bypassing prevent the rupture and promote the heal of dissection, and it was an effective surgery for the treatment of DeBakey Ⅲ dissection.
分 类 号:R318.04[医药卫生—生物医学工程]
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