基于MR分子成像的分子探针及其研究进展  

Molecular Probes and its Progress for MR Molecular Imaging

作　　者：胡丽丽[1] 宋涛[1] 杨文晖[1] 

机构地区：[1]中国科学院电工研究所,北京100190

出　　处：《北京生物医学工程》2009年第6期652-656,660,共6页Beijing Biomedical Engineering

基　　金：国家自然科学基金(50707033)资助

摘　　要：MR分子成像可以利用MRI技术并借助对比剂的生化特征来直接或间接地反映目的基因的情况,其核心任务的关键在于分子探针的选用。本文介绍了分子探针在MRI技术中的重要性及MR分子成像对分子探针的要求,且着重阐述了MR分子成像中分子探针的种类及其应用进展情况。MR molecular imaging, which uses magnetic resonance imaging technology by virtue of biochemistry properties of contrast agent, is able to directly or indirectly reflect the state of aim gene. However it is most important to appropriately select a proper molecular probe appropriately for MR molecular imaging. This paper introduces the importance and demanas of probes in MRI, and it reviews the kinds of MR molecular probes and their applications in clinic.

关 键 词：MR分子成像 分子探针 合成磁纳米颗粒 磁小体 

分 类 号：R318.04[医药卫生—生物医学工程]