CD105标记的微血管密度在病理性瘢痕中的应用  

Microvessel Density in Pathologic Scars Marked by CD105

作　　者：史岩[1] 

机构地区：[1]郑州大学护理学院临床教研室,郑州市450052

出　　处：《医药论坛杂志》2009年第23期33-34,共2页Journal of Medical Forum

摘　　要：目的检测CD105在病理性瘢痕中的表达,探讨CD105作为微血管标记在病理性瘢痕中的应用。方法采用免疫组化的方法,检测CD105在40例病理性瘢痕,20例非病理瘢痕以及20例正常皮肤中的表达。通过计数和统计学方法探讨CD105标记的微血管密度在病理性瘢痕中的应用。结果CD105标记的微血管密度在病理性瘢痕和非病理性瘢痕、正常皮肤中分别为(13.78±4.93)个/视野、(8.86±1.62)个/视野、(3.06±1.63)个/视野,有统计学意义(P<0.05)。结论CD105可能参与瘢痕血管的形成,可以作为病理性瘢痕微血管的标记物。Objective To research the role of CD105 in the vasoformation pathologic scars. Methods The S - P Immunohistochemistry technique was used to detect CD105. The count and statistic methods were used to research the effect of CD105 - MVD in pathologic scars. Results The MVD marked by CD105 have statistical significance between the pathologic scars group and the other two control groups （ P 〈 0.05 ）. Conclusion CD105 may participate the vasiformation of pathologic scar,and it can be used to mark MVD in pathologic scars.

关 键 词：瘢痕 CD105 微血管密度 

分 类 号：R446.8[医药卫生—诊断学]