医院感染粘质沙雷菌的耐药分析  

Investigation of antimicrobial-resistant profile of serratia marcescens from nosocomial infections

作　　者：陈坚[1] 徐春泉[1] 屠鸿翔[1] 

机构地区：[1]温州医学院附属第一医院,浙江温州325000

出　　处：《中国卫生检验杂志》2009年第12期2889-2890,共2页Chinese Journal of Health Laboratory Technology

摘　　要：目的:探讨温州地区粘质沙雷菌的耐药特点,分析标本组成及临床分布。方法:采用常规方法分离粘质沙雷菌,用全自动微生物分析仪进行菌种鉴定和药敏试验。结果:分离到粘质沙雷菌84株,来自重症监护病房(ICU)、外、内和产科,分别为34株、28株、20株和2株。其中痰液标本64株(占76.2%)、尿液标本12株(占14.3%)、脓液标本6株(占7.1%)及血液标本2株(占2.4%)。分离株对氨基糖甙类、三代头孢类、喹诺酮类、碳青霉烯类及复方磺胺甲噁唑的耐药率均<5%,对头孢唑啉、氨苄西林及呋喃妥因的耐药率分别为97.6%、88.1%、64.3%。结论:粘质沙雷菌主要分布于ICU、外和内科,痰液中检出率最高,对氨基糖甙类、三代头孢类、喹诺酮类、碳青霉烯类、复方磺胺甲噁唑及哌拉西林耐药率较低。Objective：To investigate the antimicrobial-resistant profile and distribution characteristics of serratia marcescens which were isolated from clinical specimens,analyze the difference of samples.Methods：The isolates of serratia marcescens were isolated from clinical specimens by routine methods.The identification and susceptibility test of the isolates were determined by automated microbiology analyzer.Results：84 strains of serratia marcescens were obtained from sputum（64）,urine（12）,pus（6）and blood（2）which were distributed among departments of intensive care unit（ICU）（34）,surgery（28）,internal medicine（20） and obstetrics（2）.The resistant rates of isolates to aminoglycosides,third-generation cephalosporins,quinolinones,carbapenems and compound sulfamethoxazole were all 5%,but the resistant rates of isolates to cephazolin,ampicillin and nitrofurantoin were 97.6%,88.1%,64.3%.Conclusion：Most of serratia marcescens comes from departments of ICU,surgery and internal medicine,about 76.2% isolates are detected from sputum.The resistant rates of isolates to aminoglycosides,third-generation cephalosporin,quinolinones,carbapenems and Compound Sulfamethoxazole are quite low.

关 键 词：粘质沙雷菌 构成比 耐药率 

分 类 号：R446.5[医药卫生—诊断学]