大连市5岁以下住院腹泻患儿星状病毒和轮状病毒的感染情况分析  

Study on status of diarrhea as a result of rotavirus and astrovirus infection in children below age of 5 years in Dalian

作　　者：边兴艳[1] 刘英华[1] 周力音[1] 王海涟[1] 

机构地区：[1]辽宁省大连市儿童医院,辽宁大连116012

出　　处：《中国卫生检验杂志》2009年第12期2900-2901,共2页Chinese Journal of Health Laboratory Technology

基　　金：大连市卫生局课题

摘　　要：目的:了解本地区5岁以下住院腹泻患儿星状病毒(AstV)和轮状病毒(RV)感染情况。方法:收集2008年10月至2009年3月380例5岁以下住院非细菌性腹泻患儿粪便,用酶免法(EIA)检测标本中的星状病毒和轮状病毒抗原。结果:380份标本中,星状病毒和轮状病毒的总阳性率为36.8%(140/380);星状病毒抗原阳性率为16.8%(64/380);轮状病毒抗原阳性率24.5%(93/380);轮状病毒抗原阴性标本中星状病毒抗原阳性率为16.4%(47/287),大多集中在2岁以内占91.2%(59/64)。二者共同阳性占总数的4.5%(17/380)。星状病毒抗原阳性率最高在3月份,为36.2%(17/47),与轮状病毒抗原的高峰期不同。结论:本地区婴幼儿秋冬季腹泻存在较多星状病毒感染,而且也存在星状病毒和轮状病毒同时感染的情况。不同年龄段和气候对不同病毒的易感性存在一定差异。Objective：To study epidemiological features of astrovirus（AstV） and rotavirus（RV） infection in children below the age of 5 years hospitalized for diarrhea in the Chidren′s Hospital of Dalian.Methods：Stool specimens of 380 saved from inpatients of Children′s Hospital of Dalian during the period Octobmer 2008 to March 2009,the antigen of AstV and RV was detected using enzyme-linked immunosorbent assay（ELISA）.The target population in this study was children below the age of five,which were negative for bacterial culture.Results：Of 380 samples,36.8%（140/380） were positive for AstV and RV totally;in which 16.8%（64/380） was positive for AstV and 24.5%（93/380）for RV respectively.Of 287 stool specimens negative for RV,AstV was detected in 16.4%,of which 92.1% were from patients of two years old or younger.4.5%（17/380）were positive for AstV and RV together.The peak of the positive rate for AstV was in March 2009 which was 36.2%（17/47）,there were differences in the peak time compared with RV.Conclusion：Both RV and AstV are important pathogens which cause viral gastroenteritis in young children in Dalian,but there were differences in viral susceptivity between AstV and RV at climate and age.

关 键 词：星状病毒 轮状病毒 腹泻 儿童 

分 类 号：R723.11[医药卫生—儿科]