一起腺病毒感染暴发后的流行病学调查与应急处理  

An epidemiological investigation and emergency deal on an adenovirus outbreak

作　　者：赵京生[1] 李争[1] 谢国旗[1] 段新科[1] 袁跃彬[1] 毛远丽 易伟国[1] 

机构地区：[1]解放军第152中心医院,河南平顶山467000 [2]济南军区疾病控制中心,山东济南250000

出　　处：《第四军医大学学报》2009年第23期2882-2884,共3页Journal of the Fourth Military Medical University

摘　　要：目的:探讨一起急性呼吸道感染暴发的流行特征及病因,同时采取应急处理控制疫情.方法:采用统一的流行病学个案调查表对病例进行调查,描述流行特征,依据初步结论,制定并实施一系列疾控措施;对流行区患者的咽拭子标本分离病原体,并对阳性分离株进行免疫荧光、聚合酶链反应(PCR)、电镜检测,对患者的双份血清进行中和试验.结果:2009-01/02,驻豫某部队发生传染性急性呼吸道感染症病例225例,疫情波及整个营区,2月10日形成发病高峰.病例以新兵为主(68.9%),有明显的宿舍聚集现象(44.9%),临床特征主要为发热,部分患者出现胸闷(13.8%)、呼吸困难(1.8%)症状,X线检查可发现肺部炎症(8.4%),肺实变(2.2%).采取各种措施切断空气传播途经,疫情迅速控制,16日后无新发病例.实验室检测结果为腺病毒感染.结论:发生在驻豫某部队急性呼吸道感染暴发的病原体为腺病毒,传播途径以空气传播为主,切断传播途经后疫情迅速控制.AIM：To describe the characteristics of an acute respiratory tract infection,adopt to correspond intervention measure to control epidemic situation.METHODS：Investigated every case by using the same epidemiological questionnaire to describe the epidemiological characteristics.Insulate and cure all sufferers,also insulate suspicious sufferers.To collect the specimen of the sufferer to separate and culture etiology agent;to test the Specimens by suing immunofluorescence,PCR,electron microscope technology and neutralize test to the couple serum of the cases.RESULTS：There were 225 cases.The incidence peaks occurred on February 10.Most cases were recruits（68.9%）.The clinical characteristics were fever（100%） and cough（71.6%）,some suffers had chest stuffy（13.8%） and dyspnea（1.8%）.After cut off the air dissemination,the epidemic situation quickly controled,there were new suffers since February 16.The results of laboratory examination was adenovirus infection.CONCLUSION：The agent of acute respiratory tract infection syndrome was confirmed as adenovirus,and the transmission route mainly were to contact with the aerosol in the air.

关 键 词：腺病毒 暴发 预防控制 

分 类 号：R56[医药卫生—呼吸系统]