空腹血糖受损人群葡萄糖负荷后血糖代谢特征及相关因素分析  

Analysis of risk factors and metabolism characteristics about blood glucose after glucose load in impaired fasting glucose population

作　　者：蒋升[1] 严丽君[2] 张莉[2] 王宁[1] 谢自敬[1] 

机构地区：[1]新疆医科大学第一附属医院内分泌科,乌鲁木齐市830054 [2]武警新疆总队医院

出　　处：《中华实用诊断与治疗杂志》2009年第12期1158-1160,共3页Journal of Chinese Practical Diagnosis and Therapy

基　　金：新疆维吾尔自治区自然科学基金项目(200421124)

摘　　要：目的:探讨空腹血糖受损人群葡萄糖负荷后血糖代谢特点及相关危险因素。方法:对3828例≥40岁居民进行流行病学调查,筛查出的空腹血糖受损者行75g葡萄糖粉负荷试验,分析葡萄糖负荷后2h血糖代谢情况及其相关因素。结果:在空腹血糖受损人群中,糖耐量减低的患病率为41.22%,女性25.71%高于男性15.51%;2型糖尿病患病率为20.82%,女性11.84%高于男性8.98%。回归分析显示,空腹血糖受损人群葡萄糖负荷后2h血糖升高的危险因素为空腹血糖、年龄和体质量指数。结论:空腹血糖受损阶段葡萄糖负荷后2h血糖代谢异常率高达62.04%,女性高于男性,其可控危险因素主要是超体质量。Objective To examine the risk factors and metabolism characteristics about 2 hours plasma glucose after glucose load in impaired fasting glucose population.Methods A cross-sectional study was conducted on 3828 residents above 40 years old.Oral glucose tolerance test（75g glucose） was administrated for impaired fasting glucose.The risk factors and metabolism characteristics about 2 hours plasma glucose were analyzed.Results The prevalence of impaired glucose tolerance in impaired fasting glucose population was 41.22%,and it was higher in females（25.71%） than in males（15.51%）.The prevalence of type 2 diabetes mellitus in impaired fasting glucose population was 20.82%,and it was higher in females（11.84%） than in males（8.98%）.Regression analysis revealed that the fasting plasma glucose,age and body mass index were risk factors for 2 hours plasma glucose in IFG.Conclusion The prevalence of abnormal 2 hours plasma glucose in impaired fasting glucose population is 62.04%,it was higher in females than in males.The main risk factor that can be controlled was overweight.

关 键 词：糖尿病 空腹血糖受损 葡萄糖负荷 危险因素 

分 类 号：R587.1[医药卫生—内分泌]