肝泡型包虫病的CT诊断及对阿苯达唑治疗效果的评价  

CT diagnosis of hepatic alveolar echinococcosis and evaluation after albendazole chemotherapy

作　　者：吴景全[1,2] 刘约翰[1,2] 王小根 

机构地区：[1]重庆医科大学附属第一医院放射科 [2]重庆市传染病寄生虫病研究所

出　　处：《中华放射学杂志》1998年第10期692-694,共3页Chinese Journal of Radiology

摘　　要：目的分析２１例肝泡型包虫病的ＣＴ征象，评价阿苯达唑治疗效果。方法全部病例包虫抗原皮试、血清酶联免疫吸附试验（ＥＬＩＳＡ）与包虫免疫印迹试验（Ｗｅｓｔｅｒｎｂｌｏｔｉｎｇ，ＷＢ）检测均为阳性，全部做ＣＴ扫描检查。阿苯达唑治疗后ＣＴ随访２０例。结果ＣＴ表现最常见特征为轮廓不规则，边界不清，密度不均的以低密度区为主的混合密度灶（ＣＴ值：－２５～＋４０ＨＵ），病灶区出现多少不一的钙化（ＣＴ值：＋９０～＋５５６ＨＵ）是本病突出的表现。ＣＴ影像分三型：实质型７例；假囊型６例；混合型８例。３例增强ＣＴ中２例病灶无强化，１例病灶周边呈轻度环形强化。ＣＴ随访２０例（时间１～９年，平均３．９年）中４例治愈，５例好转，５例稳定，６例恶化。结论ＣＴ扫描不但可用作肝泡型包虫病的诊断，而且可用于阿苯达唑等药物的疗效观察。Purpose To analyze the CT features and evaluate albendazole chemotherapy of hepatic alveolar echinococcosis with computed tomography(CT). Methods Twenty one patients of hepatic alvevolar echincoccosis were diagnosed by epidemiological、clinical、serological tests,and studied with US and CT. Twenty patients were followed up by CT scanning from 1 to 9 years(mean 3.9 years)after albendazole chemotherapy. Results CT scanning of liver befor treatment displayed heterogeneous hypodense lesions, with irregular,obscure contour and calcifications According to CT features, the hepatic lesions were divided into 3 forms: solid mass in 7 cases, pseudocystic in 6 cases and mixed in 8 cases. Three patients had contrast study. The hepatic lesions were not markedly enhanced, but the lesions were seen more clearly and appeared more extensive. In follow up examination of 20 cases,4 were apparently cured,5 improved,5 stiabilized, and 6 cases remained pseudocystic. Conclusion CT scanning was of value not only for diagnosis of hepatic alveolar echinococcosis,but also useful in evaluation of chemotherapeutic efficacy.

关 键 词：棘球蚴病 CT 诊断 阿苯达唑 肝泡型包虫病 

分 类 号：R532.32[医药卫生—内科学]