结节性甲状腺肿伴良恶性乳头状增生的临床病理分析  

CLINICOPATHOLOGICAL STUDY OF BENIGN AND MALIGNANT PAPILLARY HYPERPLASIA OF NODULAR GOITER

作　　者：刘军[1] 赵福弟[1] 石家琛 张桂兰[2] 杨丽芬[2] 刘良玉[3] 张继红 李江华 穆京娥 

机构地区：[1]吉林医学院病理教研室 [2]吉林省地方病第二防治研究所 [3]吉林医学院附属医院 [4]黑龙江省宝清县红兴隆电厂医院

出　　处：《中国地方病防治》1998年第5期365-366,共2页Chinese Journal of Control of Endemic Diseases

摘　　要：收集结节性甲状腺肿(简称结甲)伴良恶性乳头状增生病变81例,其中结甲伴良性乳头状增生52例,结甲伴恶性乳头状增生(结甲伴乳头状癌)21例,甲状腺乳头状腺瘤(实属结甲囊性变伴乳头状增生)8例。经常规HE染色,光镜检查,根据近期共认标准重新诊断,结果表明,良恶性乳头状增生病变乳头的结构和细胞核的形态存在明显差异。原诊断为甲状腺乳头状腺瘤8例,复查后均符合结甲囊性变伴乳头状增生。笔者认为甲状腺癌的发生与结甲伴乳头状增生有关。81 cases of benign and malignant papillary hyperplasia of nodular goiter were reexamined by means of routine HE staining and light microscope. There were significant differences in the feature of papillary and shape of nucleus between benign papillary hyperplasia and malignant papillary hyperplasia. Nodular goiter of papillary cystohyperplasia might be misdiagnosed as papillary cystoadenoma of thyroid gland , because 8 cases initially diagnosed as papillary cystoaednoma were in fact nodular goiter of papillary cyslohyperplasia by reexamination. The results showed that there might be a very close relationship between occurrence of carcinoma of the thyroid and papillary hyperplasia of nodular goiter.

关 键 词：甲状腺肿 乳头状增生 甲状腺肿瘤 病理 

分 类 号：R581.302[医药卫生—内分泌] R736.102[医药卫生—内科学]