冠心病患者大动脉扩张性对冠状动脉介入术的预后评价  

Large artery distensibility in risk stratification outcomes evaluation of patients received percutaneous coronary intervention

作　　者：李运田[1] 杜大勇[1] 柳杨[1] 李沫言[1] 

机构地区：[1]解放军305医院,北京100017

出　　处：《山东医药》2009年第41期1-3,共3页Shandong Medical Journal

基　　金：全军"十一五"医药卫生科研基金项目(06G145)。

摘　　要：目的探讨大动脉扩张性对冠心病患者经皮冠状动脉介入术（PCI）预后的评价。方法将316例行PC I治疗的冠心病患者根据颈—股脉搏波传导速度（CFPWV）分成Ⅰ组（0-10.0 m/s）、Ⅱ组（10.1-13.0 m/s）、Ⅲ组（〉13.0 m/s）,计数冠脉病变血管支数,评价冠脉病变严重程度,并随访（20.9±4.4）个月,记录主要心血管事件（MACE）。结果三组间比较,Ⅲ组年龄偏大,糖尿病、心肌梗死和高血压病史者多,C型病变和三支病变常见（P〈0.05）。Ⅲ组与Ⅰ与Ⅱ合并组比较,主要不良心血管事件（MACE）发生率显著增加（P均〈0.05）。多因素Logistic分析显示,CFPWV与MACE发生率呈正相关。结论CFPWV与冠脉病变的严重程度、PCI远期MACE发生率密切相关,是心血管疾病独立的强有力的预测因子,可用于指导临床早期干预。Objective To investigate the value of large artery distensibility in risk stratification outcomes evaluation of patients received percutaneous coronary intervention.Methods According to Carotid-Femoral pulse wave velocity（CFPWV）,316 consecutive patients who received percutaneous coronary intervention were divided into the following groups：Ⅰgroup（CFPWV 0-10.0 m/s）,Ⅱgroup（CFPWV 10.1-13.0 m/s）,Ⅲgroup（CFPWV〉13.0 m/s）.The major cardiovascular event（MACE） at follow-up period was recorded.Results ①The percentage of older patients,diabetes,hypertension,myocardial infarction,type C lesion and three artery were higher in Ⅲ group than that in other groups（all P〈0.05）.②The incidence of procedure-related complication,follow-up non-fatal myocardial infarction and revascular were significantly higher in Ⅲ group than that in Ⅰ＆Ⅱ groups（P〈0.05）.③ Multi-logistic analysis showed that CFPWV was positively related to incidences of MACE.Conclusions The severity of coronary artery stenosis and the increases in incidences of MACE are related to CFPWV.This parameter could be a marker of cardiovascular risk,instructing early intervention.

关 键 词：大动脉扩张性 冠状动脉疾病 脉搏波传导速度 主要心血管事件 血管成形术 经腔 经皮冠状动脉 

分 类 号：R541.4[医药卫生—心血管疾病]