单胚胎移植周期中胚胎质量及妊娠率分析  

Analysis of the embryo quality and pregnancy rate of single embryo transfer cycles

作　　者：印惠荣[1,2] 钱晓乔[1] 蔡令波[1] 冯婷[1] 严正杰[1] 马龙[1] 刘嘉茵[1] 

机构地区：[1]南京医科大学第一附属医院,南京210029 [2]南京医科大学第二附属医院

出　　处：《山东医药》2009年第45期28-30,共3页Shandong Medical Journal

基　　金：国家科技部973项目(2007CB948103);江苏省医学重点学科资助项目(XK200702)

摘　　要：目的探讨单胚胎移植周期中移植胚胎质量与妊娠率的关系。方法收集797个单胚胎移植周期(59个选择性新鲜单胚胎移植周期,542个非选择性新鲜单胚胎移植周期,196个冻胚单胚胎移植周期),观察选择性单胚胎移植周期与非选择性单胚胎移植周期、新鲜周期与冻胚周期及受精第3天胚胎卵裂球数目与临床妊娠情况,比较移植胚胎质量与临床妊娠率的关系。结果不同胚胎级别临床妊娠率比较有统计学差异,Ⅰ、Ⅱ级胚胎临床妊娠率高于Ⅲ、Ⅳ级(P均<0.05);受精第3天7～9细胞胚胎的妊娠率与4～5细胞相比有统计学差异(P<0.05)。结论单胚胎移植周期中,临床妊娠率与胚胎质量密切相关,选择性单胚胎移植可获得较理想的妊娠结局。Objective To study the embryo quality and pregnancy rate of single embryo transfer（SET）cycles.Methods Data of 797 SET cycles including 59 fresh cycles with elective single embryo transfer（eSET）,542 fresh cycles with compulsory single embryo transfer（eSET）and 196 frozen-thawed cycles were collected.The pregnancy rate between eSET and eSET cycles,fresh and frozen-thawed cycles and also the pregnancy rate in the embryos with different number of blastomere were analyzed.Results The grade of embryo was significantly related to pregnancy rate.The pregnancy rate was significantly higher in the embryos with 7-9 cells comparing with the embryos with 4-5 cells on day 3（P〈0.05）.Conclusions The clinical pregnancy rate is closely related to the quality of embryo in the SET cycles,eSET can be applied to women and have satisfactory outcomes.

关 键 词：胚胎质量 卵裂球 妊娠 胚胎移植 

分 类 号：R714.2[医药卫生—妇产科学]