2型糖尿病患者胆道术后的胰岛素强化治疗  

Intensive Insulin Therapy on Type 2 Diabetic Patients after Biliary Tract Surgery

作　　者：田影[1] 王简[1] 王春立[1] 翟虎[1] 尤胜义[1] 

机构地区：[1]天津医科大学总医院中西医结合外科,天津300052

出　　处：《中国中西医结合外科杂志》2009年第6期584-586,共3页Chinese Journal of Surgery of Integrated Traditional and Western Medicine

摘　　要：目的:探讨胰岛素强化治疗对2型糖尿病患者胆道术后的临床疗效。方法:72例胆道术后合并2型糖尿病患者随机分为强化治疗组和对照组各36例。强化治疗组给予强化胰岛素治疗,使血糖控制在4.4～6.1mmol/L;对照组给予常规胰岛素治疗,使血糖控制在10.0～11.1mmol/L。比较两组空腹血糖(FBG)、炎性指标及预后等。结果:强化治疗组FBG、体温、WBC明显低于对照组,抗生素使用天数、院内感染发生率、重症监护天数及术后并发症明显少于对照组,但低血糖发生率显著高于对照组,差异有统计学意义(P<0.05)。结论:糖尿病患者胆道术后强化胰岛素治疗,可降低炎性反应,并减少抗生素用量及重症监护天数,降低术后并发症,但低血糖发生率较高。Objective To investigate the clinical therapeutic effect of intensive insulin therapy on Type 2 diabetic patients after biliary tract surgery. Methods Seventy-two Type 2 diabetic patients after biliary tract surgery were randomly divided into intensive insulin therapy group （maintenance of blood glucose at a level between 4.4 and 6.1 mmol per liter; n=36） and control group （maintenance of blood glucose at a level between 10.0 and 11.1 mmol per liter; n=36）.Fasting blood sugar （FBC）.Inflammatory indicators and prognosis of the two groups were recorded and analyzed. Results FBG,body temperature and white cell count in the intensive insulin therapy group were greatly lower than those in the control group; with treatment of antibiotics,the incidence of nosocomial infection days of intensive care and postoperative complications in the intensive insulin therapy group were greatly less than those in the control group,but the incidence of hypoglycemia was much higher than that in control with statistically significant difference （P〈0.05）. Conclusion Intensive insulin therapy can reduce inflammatory response,antibiotic usage,days of intensive care and postoperative complications; however,the incidence of hypoglycemia is higher.

关 键 词：2型糖尿病 胆道疾病 胰岛素强化治疗 

分 类 号：R587.1[医药卫生—内分泌]