慢性重型肝炎患者早期预警及预后相关因素分析  

Analysis of related factors for early warning and prognosis in patients with chronic severe hepatitis

作　　者：范平[1] 江军[1] 陈仕祥[1] 熊志远[1] 陈玺卿[1] 李定国[2] 

机构地区：[1]解放军第一一三医院感染科,浙江宁波315040 [2]上海交通大学医学院附属新华医院

出　　处：《胃肠病学和肝病学杂志》2009年第12期1139-1140,共2页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的研究慢性重型肝炎患者早期预警和预后相关的重要指标。方法以凝血酶原活动度(prothrombin activity,PTa)为中心,对影响50例重型肝炎患者早期预警和预后的多个因素进行综合分析。结果慢性重型肝炎患者的病死率随PTa的降低而增加;慢性重型肝炎患者出现PTa<40%的时间早于其他影响因素;慢性重型肝炎合并感染患者的病死率较未合并感染患者明显增加(P=0.001)。结论PTa是慢性重型肝炎患者早期预警及判断预后的一种较敏感的指标。Objective To find out the main index for early warning and prognosis in patients with chronic severe hepatitis. Methods Prothrombin activity （PTa） was taken in 50 cases to analyze the factors which affected the early warning and prognosis in patients with chronic severe hepatitis. Results The mortality increased in patients with severe chronic hepatitis when the level of PTa decreased; PTa 〈40% occurred earlier in patients with severe chronic hepatitis than other factors. Mortality in patients with chronic severe hepatitis concurrent infection was significantly higher than that in patients without infection （P = 0. 001 ）. Conclusion PTa is a sensitive and specific index for the early warning and prognosis in the patients with chronic severe hepatitis.

关 键 词：慢性重型肝炎 凝血酶原测定 分析 

分 类 号：R512.6[医药卫生—内科学]