密达利杀灭山丘钉螺效果和鱼毒试验  

Mollusicidal effect and toxicity to fish with META-Li in field

作　　者：俞丽玲[1] 朱明东[1] 严晓岚[1] 林丽君[1] 徐青华[2] 郑寿贵 姜育华[2] 蒋能明 闻礼永[1] 

机构地区：[1]浙江省医学科学院寄生虫病研究所,杭州310013 [2]浙江省常山县疾病预防控制中心 [3]浙江省金东区疾病预防控制中心

出　　处：《中国血吸虫病防治杂志》2009年第6期532-534,共3页Chinese Journal of Schistosomiasis Control

摘　　要：目的在山丘地区观察密达利喷洒灭螺效果及对鱼类的毒性。方法选择钉螺孳生的山丘地区苗木地为灭螺试验现场,分为密达利试验组、氯硝柳胺乙醇胺盐对照组和空白对照组,观察灭螺效果;选择3口体积相同的水塘为鱼毒试验现场,分为密达利高、低浓度试验组和清水对照组进行鱼类毒性试验比较。结果施药后3、7、15 d,密达利组活螺平均密度为0.49、0.42、0.17只/0.1 m2,氯硝柳胺乙醇胺盐组为0.90、0.60、0.15只/0.1 m2,空白对照组为5.40、9.05、3.90只/0.1 m2,3、7、15 d时,活螺密度下降率密达利组为85.92%、50.55%和87.93%,氯硝柳胺乙醇胺盐组为67.03%、95.11%和91.76%,两组活螺平均密度下降率差异无统计学意义(P>0.05);施药后3,7 d和15 d,密达利组钉螺校正死亡率分别为89.76%、87.98%和94.10%,氯硝柳胺乙醇胺盐组为89.70%、83.22%和94.72%,空白对照组为9.24%、9.50%和15.21%,密达利组与氯硝柳胺乙醇胺盐组差异无统计学意义(P>0.05),与空白对照组差异有统计学意义(P<0.05)。密达利高、低浓度试验组和清水对照组鱼类死亡率均为0。结论山丘地区旱地使用密达利在短期内具有较好的杀螺效果,对鱼类低毒。The mollusicidal effect and toxicity to fish with META-Li in field were tested in mountain areas in Zhejiang Province.The snail control test,which had 3 groups including a META-Li group,niclosamide group and control group,were performed by the spraying method.The adjusted mortalities of snails in the META-Li group on the 3rd,7th and 15th day were 89.76%,87.98% and 94.10%,respectively,in the niclosamide group were 89.70%,83.22% and 94.72%,respectively,and there was no significant difference between the two groups（P〉0.05）,but they were decreased obviously compared with the control group,which were 9.24%,9.50% and 15.21%,respectively（P〈0.05）.The toxicity test to fish with META-Li included 3 groups,namely a high concentration META-Li group,low concentration META-Li group and control group,and none fish was dead.It is suggested META-Li has low toxicity to fish,and is suitable to snail control in aquiculture areas.

关 键 词：密达利 钉螺 药效 鱼毒 

分 类 号：R383.24[医药卫生—医学寄生虫学]