旋转冠状动脉造影的临床应用和安全性研究  

A study of the clinical utility and safety of rotational angiography in the diagnosis of coronary artery disease

作　　者：韩志华[1] 何奔[1] 何清[1] 邵琴[1] 葛恒[1] 龚兴荣[1] 江立生[1] 张清[1] 刘建平[1] 厉锦华[1] 周炜[2] 谢文毅[1] 刘佳俊[1] 

机构地区：[1]上海交通大学医学院附属仁济医院心内科,上海200001 [2]上海交通大学医学院附属仁济医院放射科,上海200001

出　　处：《临床心血管病杂志》2009年第12期893-896,共4页Journal of Clinical Cardiology

摘　　要：目的:评估旋转冠状动脉造影在冠心病诊断中的临床应用和安全性。方法:入选准备行诊断性冠状动脉造影的患者60例,随机分为标准冠状动脉造影(SA)组与旋转冠状动脉造影(RA)组。比较2组间应用造影剂和射线辐射量。结果:RA组所有患者成功行旋转冠状动脉造影。与标准SA组相比,RA组造影剂应用减少18%[(62.16±15.03)∶(76.91±20.00)ml,P=0.042],总的射线辐射量,左冠RA与SA相比,射线量减少了23%[(24.4034±8.1150)∶(31.8861±12.9449)Gycm2,P=0.0188],右冠RA与SA相比,射线量减少了27%[(3.9936±2.089)∶(5.4869±2.5002)Gycm2,P=0.0263]。RA与SA相比,总的手术时间呈缩短趋势[(374.8±136.2)∶(417.2±183.5)sec;P=0.2]。结论:旋转冠状动脉能够快速完成,安全有效,造影射线量和造影剂明显减少,可以成为评估冠心病的一种补充和/或替代方法。Objective：This study evaluates the safety and clinical utility of rotational angiography in the diagno sis of coronary artery disease. Method： We prospectively randomized 60 patients referred for diagnostic coronary angiography to either standard angiography（SA） or rotational angiography（RA）. Contrast and radiation utilization were compared between the two groups. Result：Rotational angiography was successfully completed in all subjects. There was a 18% reduction in contrast utilization in the rotational group as compared to the standard group （[62. 16±15.03] vs [76.91±20.00lint,P=0. 042）. Additionally, for LCA , there was a 23% reduction in total radia- tion exposure in the rotational group as compared to the standard group （[24. 403±8. 115 0]vs [31. 886 1±12. 944 9] Gycm2, P= 0. 0188）, and for RCA, there was a 27% reduction in total radiation exposure in the rotational group as compared to the standard group （[3. 993 6±2.089]vs [5. 486 9±2. 500 2] Gycm2,P=0.0263）. Procedure time tended to be shorter for rotational angiography （E353. 9±146. 7] vs [396.8±165.8]s;P=0.2）. Conclusion： Rotational coronary angiography can be rapidly performed in any patient and provides a significant reduction in contrast and radiation utilization while at the same time providing adequate angiographic data to complement or replace standard coronary angiography in the evaluation of coronary artery disease.

关 键 词：冠心病 旋转冠状动脉造影 放射线 造影剂 

分 类 号：R541.4[医药卫生—心血管疾病]