面中份缝牵引成骨过程中颅面骨缝的组织与形态学变化  

The histologic and morphologic changes of craniofacial sutures after trans-sutural distraction of midfacial skeleton

作　　者：金增强[1] 董忠生[2] 马骁[1] 柳春明[3] 

机构地区：[1]解放军307医院整形外科,北京100853 [2]郑州职业技术学院医学分院,河南郑州450052 [3]解放军总医院整形外科,北京100100

出　　处：《中国美容医学》2009年第12期1772-1775,共4页Chinese Journal of Aesthetic Medicine

基　　金：北京市自然科学基金(7072075)

摘　　要：目的:观察犬颅面骨缝的组织结构的改变,对经缝牵引技术作用下的颅面骨缝的生长改建进行初步探讨。方法:18只12周龄雌性反牙合京叭犬随机分为牵引成骨组12只和正常对照组6只,在牵引第5、10、15天,固定10、20天,去固定2月分别处死实验犬2只和对照犬1只,光镜下观察各骨缝的组织学和形态学变化。结果:在牵引与固定过程中,骨缝宽度逐渐增大,骨缝细胞发生分化、增殖,骨缝中出现大量新生血管,骨缝重新进行改建,形成新的骨缝。结论:受张力影响的上颌骨周围骨缝出现适应性重建。Objective To explore the effect of midfacial sutural distraction osteogenesis on the reconstruction of craniofacial sutures by observe the histologic and morphologic changes of craniofical sutures. Methods Eighteen mongrel dogs were used and randomly divided into the experimental group （n=12） and the control group （n=6）.Rigid external distractor was used for sutural distraction of the midfacial skeleton in the experimental animal. Two experimental and one control dogs were sacrificed at each interval （in the 5th,10th and 15th day of distraction, the 10th and 20th day of consolidation,60th day after completion of consolidation.）.To observe the sutural histologic and morphologic changes under the light microscope. Results During the period of distraction and consolidation, the width of sutures become large, the cells differentiate and proliferate, the amount of vessel increase, and the sutures reconstruct and shape the new structure. Conclusion The craniofacial sutures appear adaptive reconstruction under distraction.

关 键 词：面中份缝牵引 骨缝 组织学 形态学 

分 类 号：Q813.1[生物学—生物工程]