紫锥菊多糖抑制致病性大肠埃希菌细胞黏附的试验研究  

Inhibition of Escherichia coli adhesion to cell by Echinacea polysaccharide

作　　者：张红英[1] 王学兵[1] 赵现敏[1] 王亚宾[1] 陈丽颖[1] 夏平安[1] 崔保安[1] 

机构地区：[1]河南农业大学牧医工程学院,河南郑州450002

出　　处：《中国微生态学杂志》2009年第12期1088-1089,1094,共3页Chinese Journal of Microecology

基　　金：教育部博士点专项科研基金项目(20070466001);河南省基础与前沿技术研究计划项目(082300453207)

摘　　要：目的研究紫锥菊多糖能否影响致病性大肠埃希菌对细胞的黏附。方法使用PK-15细胞进行黏附试验及黏附抑制试验。结果发现紫锥菊多糖浓度为1.6 mg/m l时,对细菌黏附细胞的抑制作用最好,黏附率由50个细菌/细胞降低到6.8个细菌/细胞。结论紫锥菊多糖对致病性大肠埃希菌的细胞黏附具有抑制作用,提示该多糖具有调节肠道微生态的潜在应用价值。Objective To study the effection of Echinacea polysaccharide（EP） on Escherichia coli adhesion to cell.Method Adhesion test and inhibiting adhesion test were carried out on PK-15 cell.Result EP had the best inhibition for E.coli adhesion to PK-15 cell at 1.6 mg/ml concentration,the number of bacteria adhesion to cells were reduced from 50 per cell to 6.8 per cell.Conclusion The cell adhesion of E.coli can be inhibited by EP,which may have the potential application value in regulating of gut microflora.

关 键 词：紫锥菊多糖 大肠埃希菌 细菌黏附 

分 类 号：S853.7[农业科学—临床兽医学]