1062株酵母样真菌的分布及药敏分析  

DISTRIBUTION AND DRUG SUSCEPTIBILITY AMONG 1062 STRAINS OF YEAST-LIKE FUNGI

作　　者：黄秀琼[1] 梁敏华[1] 

机构地区：[1]佛山市中医院,广东佛山528000

出　　处：《现代医院》2009年第12期63-65,共3页Modern Hospitals

摘　　要：目的探讨医院内酵母样真菌感染的常见菌种、标本来源、临床病区分布及药敏性分析。方法血培养用血培养瓶抽血后在Bact/A lert3D血培养仪中培养,阳性后转种沙保罗培养基,其它标本直接接种于沙保罗培养基,分离纯菌,用V itek2 compact酵母菌鉴定卡进行鉴定,K-B法进行药敏试验。结果1 062株酵母样真菌以白色假丝酵母菌为主(588株),热带假丝酵母菌次之(258株),光滑假丝酵母菌位居第三(125株);标本来源中,痰占首位(422株),分离出白假丝酵母菌最多,热带假丝酵母菌次之;在分离的菌株中,标本来自ICU的占据比率较大(33.8%),并且感染白假丝酵母菌最多,其次为热带假丝酵母菌;6种抗真菌药物均具有较高敏感性,其中两性霉素B及制霉菌素敏感率达99%。结论真菌感染仍以白假丝酵母菌为主,真菌感染率明显升高,应合理应用抗生素,抗真菌药物的联合用药取得一定疗效。Objective To approach the common species,tracts source, distribution of clinical yeast - like fungal infection and analysis of its drug susceptibility. Methods The clinical tracts were isolated by the Chromagar eandida color medium and identified by Vitec2 Compact analysis systerm, the drug sensitivity was tested by the K - B diffusion method. Results Among these 1 062 strains of yeast- like fungi, Candida albicans accounted for the first highest positive percentage （588 strains） , followed by Candida tropicalis （258 strains） and Candida glabrata （ 125 strains）. Of all the isolates collected, sputum was predominant sample, the main strain species were Candida albieans, the fungal infection in intensive care unit was serious, Candida albicans was the most frequent isolated strain, Candida tropicalis accounted in the second. All the six antifungal agent have good anfifungal activity. The rates of susceptibility to nystafin and amphotericin B was 99%. Conclusion The percentage of fungal infection were increa：.,~l obviously. Among these clinical yeast - like infection, Candida albicans was the main organism. Terefore using antibiotics reasonably and are the main measures of preventing the fungal infection.

关 键 词：酵母样真菌 抗真菌药物 药物敏感试验 

分 类 号：R519[医药卫生—内科学] R691.3[医药卫生—临床医学]